Transcription and splicing: A two‐way street

RNA synthesis by RNA polymerase II and RNA processing are closely coupled during the transcription cycle of protein‐coding genes. This coupling affords opportunities for quality control and regulation of gene expression and the effects can go in both directions. For example, polymerase speed can aff...

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Veröffentlicht in:	Wiley interdisciplinary reviews. RNA 2020-09, Vol.11 (5), p.e1593-n/a
Hauptverfasser:	Tellier, Michael, Maudlin, Isabella, Murphy, Shona
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative splicing Animals Chromatin Chromatin - genetics Chromatin - metabolism DNA-directed RNA polymerase exon definition Exons Gene expression Gene Expression Regulation Gene-Environment Interaction Humans Protein Binding Quality control RNA polymerase RNA polymerase II RNA Polymerase II - metabolism RNA Precursors - genetics RNA processing RNA Splicing RNA Splicing Factors - metabolism RNA, Messenger - genetics splicing Transcription Transcription Factors - metabolism Transcription, Genetic
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