Preoperative Low Vital Capacity Influences Survival After Esophagectomy for Patients with Esophageal Carcinoma
Background Assessment of preoperative physiological status is crucial for optimizing clinical outcomes in patients undergoing surgery for esophageal carcinoma (EC). We aimed to evaluate the prognostic impact of pulmonary dysfunctions and their relationships with other physiological factors, especial...
Gespeichert in:
| Veröffentlicht in: | World journal of surgery 2020-07, Vol.44 (7), p.2305-2313 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2313 |
|---|---|
| container_issue | 7 |
| container_start_page | 2305 |
| container_title | World journal of surgery |
| container_volume | 44 |
| creator | Sugawara, Kotaro Mori, Kazuhiko Okumura, Yasuhiro Yagi, Koichi Aikou, Susumu Uemura, Yukari Yamashita, Hiroharu Seto, Yasuyuki |
| description | Background
Assessment of preoperative physiological status is crucial for optimizing clinical outcomes in patients undergoing surgery for esophageal carcinoma (EC). We aimed to evaluate the prognostic impact of pulmonary dysfunctions and their relationships with other physiological factors, especially sarcopenia, in EC patients receiving esophagectomy.
Methods
In total, 411 EC patients who underwent esophagectomy between 2006 and 2016 were retrospectively reviewed. Preoperative pulmonary functions were evaluated based on %vital capacity (%VC) and forced expiratory volume (FEV) 1.0%. The thresholds were set as the lowest quartile (99% for %VC and 68.6% for FEV1.0%) in this cohort.
Results
One hundred and two patients (24.8%) had low %VC (%VC |
| doi_str_mv | 10.1007/s00268-020-05450-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2370536929</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2408734072</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4263-2a827d45637771857e99f223466d58ce017918a2d730524099805b6ee9098f463</originalsourceid><addsrcrecordid>eNqNkUtv1DAUhS0EotPCH2CBLLFhE3r9iB2zK6M-NRKVymNpuZmb1lUSp3Yyo_n3NU0pEgvExrZ0z_l0rg8h7xh8YgD6MAFwVRXAoYBSlvl8QRZMCl5wwcVLsgChZH4zsUf2U7oDYFqBek32BGdcmAoWpL-MGAaMbvQbpKuwpT_86Fq6dIOr_bij533TTtjXmOjVFDd-k4dHzYiRHqcw3LobrMfQ7WgTIr3MFOzHRLd-vH2eP9Ji7fvQuTfkVePahG-f7gPy_eT42_KsWH09PV8erYpaciUK7iqu17JUQmvNqlKjMQ3nQiq1Lqsa8yKGVY6vtYCSSzB5l_JaIRowVSOVOCAfZ-4Qw_2EabSdTzW2resxTMlyoaEUynCTpR_-kt6FKfY5nc3kSgsJmmcVn1V1DClFbOwQfefizjKwv9qwcxs2t2Ef27CQTe-f0NN1h-tny-_vz4LPs2DrW9z9B9L-vLj6cgIgtchmMZtT9vU3GP8E_0emBxOEpEU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2408734072</pqid></control><display><type>article</type><title>Preoperative Low Vital Capacity Influences Survival After Esophagectomy for Patients with Esophageal Carcinoma</title><source>MEDLINE</source><source>SpringerNature Journals</source><source>Access via Wiley Online Library</source><creator>Sugawara, Kotaro ; Mori, Kazuhiko ; Okumura, Yasuhiro ; Yagi, Koichi ; Aikou, Susumu ; Uemura, Yukari ; Yamashita, Hiroharu ; Seto, Yasuyuki</creator><creatorcontrib>Sugawara, Kotaro ; Mori, Kazuhiko ; Okumura, Yasuhiro ; Yagi, Koichi ; Aikou, Susumu ; Uemura, Yukari ; Yamashita, Hiroharu ; Seto, Yasuyuki</creatorcontrib><description>Background
Assessment of preoperative physiological status is crucial for optimizing clinical outcomes in patients undergoing surgery for esophageal carcinoma (EC). We aimed to evaluate the prognostic impact of pulmonary dysfunctions and their relationships with other physiological factors, especially sarcopenia, in EC patients receiving esophagectomy.
Methods
In total, 411 EC patients who underwent esophagectomy between 2006 and 2016 were retrospectively reviewed. Preoperative pulmonary functions were evaluated based on %vital capacity (%VC) and forced expiratory volume (FEV) 1.0%. The thresholds were set as the lowest quartile (99% for %VC and 68.6% for FEV1.0%) in this cohort.
Results
One hundred and two patients (24.8%) had low %VC (%VC < 99%), which was significantly associated with age, comorbidity, sarcopenia and postoperative complications, while not correlating with pathological variables. The overall survival (OS) of patients in the low %VC group was significantly poorer than that of those in the high %VC group (
P
< 0.001), especially in those with pStage 0–II diseases (
P
< 0.001). In contrast, survival was not stratified by FEV1.0% (
P
= 0.80). Notably, patients with both low %VC and sarcopenia showed very poor 5-year OS (30.3%). Multivariate analysis revealed low %VC to be independently associated with poor OS (
P
= 0.03). In the cause-specific survival analyses, low %VC was an independent predictor of deaths from non-EC-related causes (
P
= 0.03).
Conclusions
Preoperative low %VC was independently associated with poor survival outcomes, especially when present in combination with sarcopenia, due to an increased risk of death from non-EC-related causes. Preoperative spirometry testing is useful for predicting long-term outcomes in EC patients undergoing esophagectomy.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/s00268-020-05450-0</identifier><identifier>PMID: 32123980</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Abdominal Surgery ; Adult ; Aged ; Aged, 80 and over ; Carcinoma - mortality ; Carcinoma - surgery ; Cardiac Surgery ; Complications ; Esophageal cancer ; Esophageal carcinoma ; Esophageal Neoplasms - mortality ; Esophageal Neoplasms - surgery ; Esophagectomy - mortality ; Esophagus ; Evaluation ; Female ; Follow-Up Studies ; Forced Expiratory Volume ; Gastrointestinal surgery ; General Surgery ; Health Status Indicators ; Humans ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Multivariate analysis ; Original Scientific Report ; Patients ; Physiological effects ; Physiological factors ; Physiology ; Postoperative Complications - epidemiology ; Postoperative Complications - etiology ; Preoperative Period ; Prognosis ; Pulmonary functions ; Retrospective Studies ; Risk Factors ; Sarcopenia ; Sarcopenia - epidemiology ; Sarcopenia - etiology ; Surgery ; Survival ; Survival Analysis ; Thoracic Surgery ; Vascular Surgery ; Vital Capacity</subject><ispartof>World journal of surgery, 2020-07, Vol.44 (7), p.2305-2313</ispartof><rights>Société Internationale de Chirurgie 2020</rights><rights>2020 The Author(s) under exclusive licence to Société Internationale de Chirurgie</rights><rights>Société Internationale de Chirurgie 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4263-2a827d45637771857e99f223466d58ce017918a2d730524099805b6ee9098f463</citedby><cites>FETCH-LOGICAL-c4263-2a827d45637771857e99f223466d58ce017918a2d730524099805b6ee9098f463</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00268-020-05450-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00268-020-05450-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,41488,42557,45574,45575,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32123980$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sugawara, Kotaro</creatorcontrib><creatorcontrib>Mori, Kazuhiko</creatorcontrib><creatorcontrib>Okumura, Yasuhiro</creatorcontrib><creatorcontrib>Yagi, Koichi</creatorcontrib><creatorcontrib>Aikou, Susumu</creatorcontrib><creatorcontrib>Uemura, Yukari</creatorcontrib><creatorcontrib>Yamashita, Hiroharu</creatorcontrib><creatorcontrib>Seto, Yasuyuki</creatorcontrib><title>Preoperative Low Vital Capacity Influences Survival After Esophagectomy for Patients with Esophageal Carcinoma</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><addtitle>World J Surg</addtitle><description>Background
Assessment of preoperative physiological status is crucial for optimizing clinical outcomes in patients undergoing surgery for esophageal carcinoma (EC). We aimed to evaluate the prognostic impact of pulmonary dysfunctions and their relationships with other physiological factors, especially sarcopenia, in EC patients receiving esophagectomy.
Methods
In total, 411 EC patients who underwent esophagectomy between 2006 and 2016 were retrospectively reviewed. Preoperative pulmonary functions were evaluated based on %vital capacity (%VC) and forced expiratory volume (FEV) 1.0%. The thresholds were set as the lowest quartile (99% for %VC and 68.6% for FEV1.0%) in this cohort.
Results
One hundred and two patients (24.8%) had low %VC (%VC < 99%), which was significantly associated with age, comorbidity, sarcopenia and postoperative complications, while not correlating with pathological variables. The overall survival (OS) of patients in the low %VC group was significantly poorer than that of those in the high %VC group (
P
< 0.001), especially in those with pStage 0–II diseases (
P
< 0.001). In contrast, survival was not stratified by FEV1.0% (
P
= 0.80). Notably, patients with both low %VC and sarcopenia showed very poor 5-year OS (30.3%). Multivariate analysis revealed low %VC to be independently associated with poor OS (
P
= 0.03). In the cause-specific survival analyses, low %VC was an independent predictor of deaths from non-EC-related causes (
P
= 0.03).
Conclusions
Preoperative low %VC was independently associated with poor survival outcomes, especially when present in combination with sarcopenia, due to an increased risk of death from non-EC-related causes. Preoperative spirometry testing is useful for predicting long-term outcomes in EC patients undergoing esophagectomy.</description><subject>Abdominal Surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Carcinoma - mortality</subject><subject>Carcinoma - surgery</subject><subject>Cardiac Surgery</subject><subject>Complications</subject><subject>Esophageal cancer</subject><subject>Esophageal carcinoma</subject><subject>Esophageal Neoplasms - mortality</subject><subject>Esophageal Neoplasms - surgery</subject><subject>Esophagectomy - mortality</subject><subject>Esophagus</subject><subject>Evaluation</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Forced Expiratory Volume</subject><subject>Gastrointestinal surgery</subject><subject>General Surgery</subject><subject>Health Status Indicators</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multivariate analysis</subject><subject>Original Scientific Report</subject><subject>Patients</subject><subject>Physiological effects</subject><subject>Physiological factors</subject><subject>Physiology</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - etiology</subject><subject>Preoperative Period</subject><subject>Prognosis</subject><subject>Pulmonary functions</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sarcopenia</subject><subject>Sarcopenia - epidemiology</subject><subject>Sarcopenia - etiology</subject><subject>Surgery</subject><subject>Survival</subject><subject>Survival Analysis</subject><subject>Thoracic Surgery</subject><subject>Vascular Surgery</subject><subject>Vital Capacity</subject><issn>0364-2313</issn><issn>1432-2323</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkUtv1DAUhS0EotPCH2CBLLFhE3r9iB2zK6M-NRKVymNpuZmb1lUSp3Yyo_n3NU0pEgvExrZ0z_l0rg8h7xh8YgD6MAFwVRXAoYBSlvl8QRZMCl5wwcVLsgChZH4zsUf2U7oDYFqBek32BGdcmAoWpL-MGAaMbvQbpKuwpT_86Fq6dIOr_bij533TTtjXmOjVFDd-k4dHzYiRHqcw3LobrMfQ7WgTIr3MFOzHRLd-vH2eP9Ji7fvQuTfkVePahG-f7gPy_eT42_KsWH09PV8erYpaciUK7iqu17JUQmvNqlKjMQ3nQiq1Lqsa8yKGVY6vtYCSSzB5l_JaIRowVSOVOCAfZ-4Qw_2EabSdTzW2resxTMlyoaEUynCTpR_-kt6FKfY5nc3kSgsJmmcVn1V1DClFbOwQfefizjKwv9qwcxs2t2Ef27CQTe-f0NN1h-tny-_vz4LPs2DrW9z9B9L-vLj6cgIgtchmMZtT9vU3GP8E_0emBxOEpEU</recordid><startdate>202007</startdate><enddate>202007</enddate><creator>Sugawara, Kotaro</creator><creator>Mori, Kazuhiko</creator><creator>Okumura, Yasuhiro</creator><creator>Yagi, Koichi</creator><creator>Aikou, Susumu</creator><creator>Uemura, Yukari</creator><creator>Yamashita, Hiroharu</creator><creator>Seto, Yasuyuki</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>202007</creationdate><title>Preoperative Low Vital Capacity Influences Survival After Esophagectomy for Patients with Esophageal Carcinoma</title><author>Sugawara, Kotaro ; Mori, Kazuhiko ; Okumura, Yasuhiro ; Yagi, Koichi ; Aikou, Susumu ; Uemura, Yukari ; Yamashita, Hiroharu ; Seto, Yasuyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4263-2a827d45637771857e99f223466d58ce017918a2d730524099805b6ee9098f463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Abdominal Surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Carcinoma - mortality</topic><topic>Carcinoma - surgery</topic><topic>Cardiac Surgery</topic><topic>Complications</topic><topic>Esophageal cancer</topic><topic>Esophageal carcinoma</topic><topic>Esophageal Neoplasms - mortality</topic><topic>Esophageal Neoplasms - surgery</topic><topic>Esophagectomy - mortality</topic><topic>Esophagus</topic><topic>Evaluation</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Forced Expiratory Volume</topic><topic>Gastrointestinal surgery</topic><topic>General Surgery</topic><topic>Health Status Indicators</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Multivariate analysis</topic><topic>Original Scientific Report</topic><topic>Patients</topic><topic>Physiological effects</topic><topic>Physiological factors</topic><topic>Physiology</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - etiology</topic><topic>Preoperative Period</topic><topic>Prognosis</topic><topic>Pulmonary functions</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sarcopenia</topic><topic>Sarcopenia - epidemiology</topic><topic>Sarcopenia - etiology</topic><topic>Surgery</topic><topic>Survival</topic><topic>Survival Analysis</topic><topic>Thoracic Surgery</topic><topic>Vascular Surgery</topic><topic>Vital Capacity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sugawara, Kotaro</creatorcontrib><creatorcontrib>Mori, Kazuhiko</creatorcontrib><creatorcontrib>Okumura, Yasuhiro</creatorcontrib><creatorcontrib>Yagi, Koichi</creatorcontrib><creatorcontrib>Aikou, Susumu</creatorcontrib><creatorcontrib>Uemura, Yukari</creatorcontrib><creatorcontrib>Yamashita, Hiroharu</creatorcontrib><creatorcontrib>Seto, Yasuyuki</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>World journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sugawara, Kotaro</au><au>Mori, Kazuhiko</au><au>Okumura, Yasuhiro</au><au>Yagi, Koichi</au><au>Aikou, Susumu</au><au>Uemura, Yukari</au><au>Yamashita, Hiroharu</au><au>Seto, Yasuyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preoperative Low Vital Capacity Influences Survival After Esophagectomy for Patients with Esophageal Carcinoma</atitle><jtitle>World journal of surgery</jtitle><stitle>World J Surg</stitle><addtitle>World J Surg</addtitle><date>2020-07</date><risdate>2020</risdate><volume>44</volume><issue>7</issue><spage>2305</spage><epage>2313</epage><pages>2305-2313</pages><issn>0364-2313</issn><eissn>1432-2323</eissn><abstract>Background
Assessment of preoperative physiological status is crucial for optimizing clinical outcomes in patients undergoing surgery for esophageal carcinoma (EC). We aimed to evaluate the prognostic impact of pulmonary dysfunctions and their relationships with other physiological factors, especially sarcopenia, in EC patients receiving esophagectomy.
Methods
In total, 411 EC patients who underwent esophagectomy between 2006 and 2016 were retrospectively reviewed. Preoperative pulmonary functions were evaluated based on %vital capacity (%VC) and forced expiratory volume (FEV) 1.0%. The thresholds were set as the lowest quartile (99% for %VC and 68.6% for FEV1.0%) in this cohort.
Results
One hundred and two patients (24.8%) had low %VC (%VC < 99%), which was significantly associated with age, comorbidity, sarcopenia and postoperative complications, while not correlating with pathological variables. The overall survival (OS) of patients in the low %VC group was significantly poorer than that of those in the high %VC group (
P
< 0.001), especially in those with pStage 0–II diseases (
P
< 0.001). In contrast, survival was not stratified by FEV1.0% (
P
= 0.80). Notably, patients with both low %VC and sarcopenia showed very poor 5-year OS (30.3%). Multivariate analysis revealed low %VC to be independently associated with poor OS (
P
= 0.03). In the cause-specific survival analyses, low %VC was an independent predictor of deaths from non-EC-related causes (
P
= 0.03).
Conclusions
Preoperative low %VC was independently associated with poor survival outcomes, especially when present in combination with sarcopenia, due to an increased risk of death from non-EC-related causes. Preoperative spirometry testing is useful for predicting long-term outcomes in EC patients undergoing esophagectomy.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>32123980</pmid><doi>10.1007/s00268-020-05450-0</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0364-2313 |
| ispartof | World journal of surgery, 2020-07, Vol.44 (7), p.2305-2313 |
| issn | 0364-2313 1432-2323 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2370536929 |
| source | MEDLINE; SpringerNature Journals; Access via Wiley Online Library |
| subjects | Abdominal Surgery Adult Aged Aged, 80 and over Carcinoma - mortality Carcinoma - surgery Cardiac Surgery Complications Esophageal cancer Esophageal carcinoma Esophageal Neoplasms - mortality Esophageal Neoplasms - surgery Esophagectomy - mortality Esophagus Evaluation Female Follow-Up Studies Forced Expiratory Volume Gastrointestinal surgery General Surgery Health Status Indicators Humans Male Medicine Medicine & Public Health Middle Aged Multivariate analysis Original Scientific Report Patients Physiological effects Physiological factors Physiology Postoperative Complications - epidemiology Postoperative Complications - etiology Preoperative Period Prognosis Pulmonary functions Retrospective Studies Risk Factors Sarcopenia Sarcopenia - epidemiology Sarcopenia - etiology Surgery Survival Survival Analysis Thoracic Surgery Vascular Surgery Vital Capacity |
| title | Preoperative Low Vital Capacity Influences Survival After Esophagectomy for Patients with Esophageal Carcinoma |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T21%3A18%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Preoperative%20Low%20Vital%20Capacity%20Influences%20Survival%20After%20Esophagectomy%20for%20Patients%20with%20Esophageal%20Carcinoma&rft.jtitle=World%20journal%20of%20surgery&rft.au=Sugawara,%20Kotaro&rft.date=2020-07&rft.volume=44&rft.issue=7&rft.spage=2305&rft.epage=2313&rft.pages=2305-2313&rft.issn=0364-2313&rft.eissn=1432-2323&rft_id=info:doi/10.1007/s00268-020-05450-0&rft_dat=%3Cproquest_cross%3E2408734072%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2408734072&rft_id=info:pmid/32123980&rfr_iscdi=true |