Impact of graft‐versus‐host disease and graft‐versus‐leukemia effect based on minimal residual disease in Philadelphia chromosome‐positive acute lymphoblastic leukemia

Summary The impacts of graft‐versus‐host disease (GVHD) and graft‐versus‐leukemia (GVL) effect might differ depending on minimal residual disease (MRD). Therefore, we examined 1,022 recipients who underwent their first allogeneic hematopoietic stem cell transplantation (HSCT) for Philadelphia chromo...

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Veröffentlicht in:	British journal of haematology 2020-07, Vol.190 (1), p.84-92
Hauptverfasser:	Akahoshi, Yu, Igarashi, Aiko, Fukuda, Takahiro, Uchida, Naoyuki, Tanaka, Masatsugu, Ozawa, Yukiyasu, Kanda, Yoshinobu, Onizuka, Makoto, Ichinohe, Tatsuo, Tanaka, Junji, Atsuta, Yoshiko, Kako, Shinichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lymphoblastic leukemia Adolescent Adult Aged Female Graft vs Host Disease - immunology Graft vs Leukemia Effect - immunology Graft-versus-host reaction graft‐versus‐host disease graft‐versus‐leukemia effect Hematology Hematopoietic stem cells Humans Leukemia Lymphatic leukemia Male Middle Aged Minimal residual disease Mortality Neoplasm, Residual - complications Philadelphia chromosome Philadelphia chromosome‐positive acute lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Prophylaxis Remission Stem cell transplantation Transplants & implants tyrosine kinase inhibitor Young Adult
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