Use of targeting therapy in Erdheim-Chester disease: A case report with neurologic involvement

Erdheim-Chester disease (ECD) is a rare multisystemic disease characterised by an infiltration of various organs by CD68 CD1a histiocytes. The clinical and radiological presentation is very variable. We report the case of a 71-year-old woman with ECD which was revealed by neurological and cutaneous...

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Veröffentlicht in:	La revue de medecine interne 2020-06, Vol.41 (6), p.413-417
Hauptverfasser:	Berthe, P, Rouzic, N, Daelman, L, Jacobzone, C, Espitia, A, Cohen-Aubart, F, Haroche, J, Émile, J-F, Lorleac'h, A
Format:	Artikel
Sprache:	fre
Schlagworte:	Aged Azetidines - administration & dosage Drug Therapy, Combination Erdheim-Chester Disease - complications Erdheim-Chester Disease - diagnosis Erdheim-Chester Disease - drug therapy Female Humans Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors Molecular Targeted Therapy - methods Nervous System Diseases - diagnosis Nervous System Diseases - drug therapy Nervous System Diseases - etiology Piperidines - administration & dosage Protein Kinase Inhibitors - administration & dosage Proto-Oncogene Proteins B-raf - antagonists & inhibitors Proto-Oncogene Proteins B-raf - genetics Rare Diseases Skin Diseases - diagnosis Skin Diseases - etiology Skin Diseases - pathology Skin Diseases - therapy Vemurafenib - administration & dosage
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