Coordination of germ layer lineage choice by TET1 during primed pluripotency

Gastrulation in the early postimplantation stage mammalian embryo begins when epiblast cells ingress to form the primitive streak or develop as the embryonic ectoderm. The DNA dioxygenase Tet1 is highly expressed in the epiblast and yet continues to regulate lineage specification during gastrulation...

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Veröffentlicht in:	Genes & development 2020-04, Vol.34 (7-8), p.598-618
Hauptverfasser:	Luo, Xinlong, van der Veer, Bernard K, Sun, Lei, Bartoccetti, Michela, Boretto, Matteo, Vankelecom, Hugo, Khoueiry, Rita, Koh, Kian Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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