$Theophylline adenosine dipyridamole (CTAD) and citrate evaluation to survey unfractionated heparin treatment: a delayed centrifugation validation for anti-Xa measurement?$

Theophylline adenosine dipyridamole (CTAD) and citrate evaluation to survey unfractionated heparin treatment: a delayed centrifugation validation for anti-Xa measurement?

Unfractionated heparin (UFH) is the main anticoagulante used in intensive care unit. The anticoagulant effect is monitored by activated partial thrombin time (aPTT) and anti-Xa activity (anti-Xa) measurement. However, delayed centrifugation induces platelet factor 4 (PF4) release and anti-Xa decreas...

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Veröffentlicht in:	Annales de biologie clinique (Paris) 2020-02, Vol.78 (1), p.27-34
Hauptverfasser:	Billoir, Paul, Clavier, Thomas, Guilbert, Arnaud, Barbay, Virginie, Chrétien, Marie Hélène, Fresel, Marielle, Abriou, Caroline, Girault, Christophe, Le Cam Duchez, Véronique
Format:	Artikel
Sprache:	fre
Schlagworte:	Adenosine - chemistry Adenosine - pharmacology Anticoagulants - chemistry Anticoagulants - pharmacology Anticoagulants - therapeutic use Blood Coagulation Tests - methods Blood Preservation - methods Blood Specimen Collection - methods Centrifugation - methods Chemical Fractionation - methods Citric Acid - chemistry Citric Acid - pharmacology Dipyridamole - chemistry Dipyridamole - pharmacology Drug Monitoring - methods Factor Xa - metabolism Factor Xa Inhibitors - analysis Factor Xa Inhibitors - blood Heparin - analysis Heparin - therapeutic use Humans Partial Thromboplastin Time Theophylline - chemistry Theophylline - pharmacology Thrombin Time Time Factors
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