A New Clinical and Immunovirological Score for Predicting the Risk of Late Severe Infection in Solid Organ Transplant Recipients: The CLIV Score

Abstract Background We aimed at constructing a composite score based on Epstein-Barr virus DNAemia (EBVd) and simple clinical and immunological parameters to predict late severe infection (LI) beyond month 6 in solid organ transplantation (SOT) recipients. Methods Kidney and liver transplant recipie...

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Veröffentlicht in:	The Journal of infectious diseases 2020-07, Vol.222 (3), p.479-487
Hauptverfasser:	San-Juan, Rafael, Fernández-Ruiz, Mario, Ruiz-Ruigómez, María, López-Medrano, Francisco, Ruiz-Merlo, Tamara, Andrés, Amado, Loinaz, Carmelo, Len, Oscar, Azancot, María Antonieta, Montejo, Miguel, Rodriguez-Alvarez, Regino, Fortún, Jesús, Escudero-Sánchez, Rosa, Giménez, Estela, Lora, David, Albert, Eliseo, Navarro, David, Aguado, José María
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged CD8 antigen CD8-Positive T-Lymphocytes - immunology Cytomegalovirus DNA, Viral - blood Epstein-Barr virus Epstein-Barr Virus Infections - diagnosis Epstein-Barr Virus Infections - virology Female Herpesvirus 4, Human - isolation & purification Humans Immunoglobulins Immunosuppression Infections Kidney transplantation Leukocyte Count Liver transplantation Lymphocytes T Male Middle Aged Multivariate Analysis Opportunistic Infections - etiology Organ Transplantation - adverse effects Peripheral blood Postoperative Complications - etiology Recurrent infection ROC Curve Transplants & implants
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