Access to Unnatural α‑Amino Acids via Visible-Light-Mediated Decarboxylative Conjugate Addition to Dehydroalanine

An expedient synthesis of β-alkyl α-amino acids is reported via application of decarboxylative photocatalysis. The method utilizes abundant, diverse, and inexpensive carboxylic acids to provide radicals for conjugate addition to dehydroalanine ester. High-throughput experimentation revealed an acrid...

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Veröffentlicht in:	Organic letters 2020-03, Vol.22 (6), p.2196-2200
Hauptverfasser:	Shah, Akshay A, Kelly, Michael J, Perkins, James J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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