Risk factors for stage underestimation in patients with clinical T1N0 gastric cancer
Purpose Limited gastrectomy has been generally performed in clinical T1N0 gastric cancer. The aim of this study was to identify risk factors for stage underestimation in clinical T1N0 gastric cancer. Methods This study reviewed the medical records of 566 patients who underwent gastrectomy for clinic...
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| Veröffentlicht in: | Surgery today (Tokyo, Japan) Japan), 2020-09, Vol.50 (9), p.1074-1080 |
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| container_title | Surgery today (Tokyo, Japan) |
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| creator | Kunishige, Tomohiro Migita, Kazuhiro Matsumoto, Sohei Wakatsuki, Kohei Nakade, Hiroshi Miyao, Shintaro Sho, Masayuki |
| description | Purpose
Limited gastrectomy has been generally performed in clinical T1N0 gastric cancer. The aim of this study was to identify risk factors for stage underestimation in clinical T1N0 gastric cancer.
Methods
This study reviewed the medical records of 566 patients who underwent gastrectomy for clinical T1N0 gastric cancer.
Results
The tumor stage was underestimated in 122 (21.6%) patients. The relapse-free survival rate was significantly lower in the patients with pathological stage II (
P
= 0.021) and III (
P
|
| doi_str_mv | 10.1007/s00595-020-01984-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2369407002</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2369407002</sourcerecordid><originalsourceid>FETCH-LOGICAL-c371t-619bfe49ecb0ecaebe3bd796d07a31ebec572af6b74a651bfda67f1c4542b4313</originalsourceid><addsrcrecordid>eNp9kE9PwzAMxSMEYmPwBTigHLkU7CRt1iOa-CchkNA4R2majowuHUkrxrcnsMGRk235-cnvR8gpwgUCyMsIkJd5BgwywHIqss0eGaPgRcamyPfJGEqBGbISR-QoxiUAE1OAQzLiDEEWgo_J_NnFN9po03ch0qYLNPZ6Yengaxts7N1K967z1Hm6Tp31faQfrn-lpnXeGd3SOT4CXejYB2eo0d7YcEwOGt1Ge7KrE_Jycz2f3WUPT7f3s6uHzHCJfVZgWTVWlNZUYI22leVVLcuiBqk5ptHkkummqKTQRY5VU-tCNmhELlglOPIJOd_6rkP3PqRv1cpFY9tWe9sNUTFelAJkyp2kbCs1oYsx2EatQ8oWPhWC-qaptjRVoql-aKpNOjrb-Q_VytZ_J7_4koBvBTGt_MIGteyG4FPm_2y_ALr0gag</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2369407002</pqid></control><display><type>article</type><title>Risk factors for stage underestimation in patients with clinical T1N0 gastric cancer</title><source>SpringerLink</source><creator>Kunishige, Tomohiro ; Migita, Kazuhiro ; Matsumoto, Sohei ; Wakatsuki, Kohei ; Nakade, Hiroshi ; Miyao, Shintaro ; Sho, Masayuki</creator><creatorcontrib>Kunishige, Tomohiro ; Migita, Kazuhiro ; Matsumoto, Sohei ; Wakatsuki, Kohei ; Nakade, Hiroshi ; Miyao, Shintaro ; Sho, Masayuki</creatorcontrib><description>Purpose
Limited gastrectomy has been generally performed in clinical T1N0 gastric cancer. The aim of this study was to identify risk factors for stage underestimation in clinical T1N0 gastric cancer.
Methods
This study reviewed the medical records of 566 patients who underwent gastrectomy for clinical T1N0 gastric cancer.
Results
The tumor stage was underestimated in 122 (21.6%) patients. The relapse-free survival rate was significantly lower in the patients with pathological stage II (
P
= 0.021) and III (
P
< 0.001) disease than in those with pathological stage IA disease. In the multivariate analysis, a location in the upper third of the stomach, tumor size of ≥ 30 mm, undifferentiated adenocarcinoma and clinical tumor depth of SM were identified as independent risk factors for pathological stages II and III. The rate of pathological stages II and III was 0% in the patients with no risk factors, 3% in those with 1 risk factor, 10.5% in those with 2 risk factors, 19.8% in those with 3 risk factors and 50% in those with 4 risk factors.
Conclusions
Location, tumor size, undifferentiated adenocarcinoma and clinical tumor depth were independent risk factors for pathological stages II and III in clinical T1N0 gastric cancer.</description><identifier>ISSN: 0941-1291</identifier><identifier>EISSN: 1436-2813</identifier><identifier>DOI: 10.1007/s00595-020-01984-x</identifier><identifier>PMID: 32107643</identifier><language>eng</language><publisher>Singapore: Springer Singapore</publisher><subject>Medicine ; Medicine & Public Health ; Original Article ; Surgery ; Surgical Oncology</subject><ispartof>Surgery today (Tokyo, Japan), 2020-09, Vol.50 (9), p.1074-1080</ispartof><rights>Springer Nature Singapore Pte Ltd. 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-619bfe49ecb0ecaebe3bd796d07a31ebec572af6b74a651bfda67f1c4542b4313</citedby><cites>FETCH-LOGICAL-c371t-619bfe49ecb0ecaebe3bd796d07a31ebec572af6b74a651bfda67f1c4542b4313</cites><orcidid>0000-0003-0600-3117</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00595-020-01984-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00595-020-01984-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27926,27927,41490,42559,51321</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32107643$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kunishige, Tomohiro</creatorcontrib><creatorcontrib>Migita, Kazuhiro</creatorcontrib><creatorcontrib>Matsumoto, Sohei</creatorcontrib><creatorcontrib>Wakatsuki, Kohei</creatorcontrib><creatorcontrib>Nakade, Hiroshi</creatorcontrib><creatorcontrib>Miyao, Shintaro</creatorcontrib><creatorcontrib>Sho, Masayuki</creatorcontrib><title>Risk factors for stage underestimation in patients with clinical T1N0 gastric cancer</title><title>Surgery today (Tokyo, Japan)</title><addtitle>Surg Today</addtitle><addtitle>Surg Today</addtitle><description>Purpose
Limited gastrectomy has been generally performed in clinical T1N0 gastric cancer. The aim of this study was to identify risk factors for stage underestimation in clinical T1N0 gastric cancer.
Methods
This study reviewed the medical records of 566 patients who underwent gastrectomy for clinical T1N0 gastric cancer.
Results
The tumor stage was underestimated in 122 (21.6%) patients. The relapse-free survival rate was significantly lower in the patients with pathological stage II (
P
= 0.021) and III (
P
< 0.001) disease than in those with pathological stage IA disease. In the multivariate analysis, a location in the upper third of the stomach, tumor size of ≥ 30 mm, undifferentiated adenocarcinoma and clinical tumor depth of SM were identified as independent risk factors for pathological stages II and III. The rate of pathological stages II and III was 0% in the patients with no risk factors, 3% in those with 1 risk factor, 10.5% in those with 2 risk factors, 19.8% in those with 3 risk factors and 50% in those with 4 risk factors.
Conclusions
Location, tumor size, undifferentiated adenocarcinoma and clinical tumor depth were independent risk factors for pathological stages II and III in clinical T1N0 gastric cancer.</description><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Article</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><issn>0941-1291</issn><issn>1436-2813</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kE9PwzAMxSMEYmPwBTigHLkU7CRt1iOa-CchkNA4R2majowuHUkrxrcnsMGRk235-cnvR8gpwgUCyMsIkJd5BgwywHIqss0eGaPgRcamyPfJGEqBGbISR-QoxiUAE1OAQzLiDEEWgo_J_NnFN9po03ch0qYLNPZ6Yengaxts7N1K967z1Hm6Tp31faQfrn-lpnXeGd3SOT4CXejYB2eo0d7YcEwOGt1Ge7KrE_Jycz2f3WUPT7f3s6uHzHCJfVZgWTVWlNZUYI22leVVLcuiBqk5ptHkkummqKTQRY5VU-tCNmhELlglOPIJOd_6rkP3PqRv1cpFY9tWe9sNUTFelAJkyp2kbCs1oYsx2EatQ8oWPhWC-qaptjRVoql-aKpNOjrb-Q_VytZ_J7_4koBvBTGt_MIGteyG4FPm_2y_ALr0gag</recordid><startdate>20200901</startdate><enddate>20200901</enddate><creator>Kunishige, Tomohiro</creator><creator>Migita, Kazuhiro</creator><creator>Matsumoto, Sohei</creator><creator>Wakatsuki, Kohei</creator><creator>Nakade, Hiroshi</creator><creator>Miyao, Shintaro</creator><creator>Sho, Masayuki</creator><general>Springer Singapore</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0600-3117</orcidid></search><sort><creationdate>20200901</creationdate><title>Risk factors for stage underestimation in patients with clinical T1N0 gastric cancer</title><author>Kunishige, Tomohiro ; Migita, Kazuhiro ; Matsumoto, Sohei ; Wakatsuki, Kohei ; Nakade, Hiroshi ; Miyao, Shintaro ; Sho, Masayuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-619bfe49ecb0ecaebe3bd796d07a31ebec572af6b74a651bfda67f1c4542b4313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Article</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kunishige, Tomohiro</creatorcontrib><creatorcontrib>Migita, Kazuhiro</creatorcontrib><creatorcontrib>Matsumoto, Sohei</creatorcontrib><creatorcontrib>Wakatsuki, Kohei</creatorcontrib><creatorcontrib>Nakade, Hiroshi</creatorcontrib><creatorcontrib>Miyao, Shintaro</creatorcontrib><creatorcontrib>Sho, Masayuki</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery today (Tokyo, Japan)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kunishige, Tomohiro</au><au>Migita, Kazuhiro</au><au>Matsumoto, Sohei</au><au>Wakatsuki, Kohei</au><au>Nakade, Hiroshi</au><au>Miyao, Shintaro</au><au>Sho, Masayuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk factors for stage underestimation in patients with clinical T1N0 gastric cancer</atitle><jtitle>Surgery today (Tokyo, Japan)</jtitle><stitle>Surg Today</stitle><addtitle>Surg Today</addtitle><date>2020-09-01</date><risdate>2020</risdate><volume>50</volume><issue>9</issue><spage>1074</spage><epage>1080</epage><pages>1074-1080</pages><issn>0941-1291</issn><eissn>1436-2813</eissn><abstract>Purpose
Limited gastrectomy has been generally performed in clinical T1N0 gastric cancer. The aim of this study was to identify risk factors for stage underestimation in clinical T1N0 gastric cancer.
Methods
This study reviewed the medical records of 566 patients who underwent gastrectomy for clinical T1N0 gastric cancer.
Results
The tumor stage was underestimated in 122 (21.6%) patients. The relapse-free survival rate was significantly lower in the patients with pathological stage II (
P
= 0.021) and III (
P
< 0.001) disease than in those with pathological stage IA disease. In the multivariate analysis, a location in the upper third of the stomach, tumor size of ≥ 30 mm, undifferentiated adenocarcinoma and clinical tumor depth of SM were identified as independent risk factors for pathological stages II and III. The rate of pathological stages II and III was 0% in the patients with no risk factors, 3% in those with 1 risk factor, 10.5% in those with 2 risk factors, 19.8% in those with 3 risk factors and 50% in those with 4 risk factors.
Conclusions
Location, tumor size, undifferentiated adenocarcinoma and clinical tumor depth were independent risk factors for pathological stages II and III in clinical T1N0 gastric cancer.</abstract><cop>Singapore</cop><pub>Springer Singapore</pub><pmid>32107643</pmid><doi>10.1007/s00595-020-01984-x</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-0600-3117</orcidid></addata></record> |
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| ispartof | Surgery today (Tokyo, Japan), 2020-09, Vol.50 (9), p.1074-1080 |
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| language | eng |
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| subjects | Medicine Medicine & Public Health Original Article Surgery Surgical Oncology |
| title | Risk factors for stage underestimation in patients with clinical T1N0 gastric cancer |
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