Leucine and mTORc1 act independently to regulate 2-deoxyglucose uptake in L6 myotubes
Chronic mTORc1 hyperactivation via obesity-induced hyperleucinaemia has been implicated in the development of insulin resistance, yet the direct impact of leucine on insulin-stimulated glucose uptake in muscle cells remains unclear. To address this, differentiated L6 myotubes were subjected to vario...
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Veröffentlicht in: | Amino acids 2020-03, Vol.52 (3), p.477-486 |
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