Adverse Effects of Circadian Disorganization on Mood and Molecular Rhythms in the Prefrontal Cortex of Mice

•Exposure to a disrupted light–dark cycle alters mood-related behaviors in mice.•Clock genes are abundantly expressed in the prefrontal cortex of mice.•Circadian disorganization alters rhythmic expression of clock and immediate early genes in the prefrontal cortex of mice.•The prefrontal cortex may...

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Veröffentlicht in:	Neuroscience 2020-04, Vol.432, p.44-54
Hauptverfasser:	Otsuka, Tsuyoshi, Thi Le, Hue, Kohsaka, Akira, Sato, Fuyuki, Ihara, Hayato, Nakao, Tomomi, Maeda, Masanobu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Circadian Clocks circadian disorganization Circadian Rhythm clock gene Male Mice Mice, Inbred C57BL mood Prefrontal Cortex shift work Sleep Wakefulness
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