Improved Mycobacterium tuberculosis clearance after the restoration of IFN‐γ+TNF‐α+CD4+T cells: Impact of PD‐1 inhibition in active tuberculosis patients

Prolonged therapy, drug toxicity, noncompliance, immune suppression, and alarming emergence of drug resistance necessitate the search for therapeutic vaccine strategies for tuberculosis (TB). Such strategies ought to elicit not only IFN‐γ, but polyfunctional response including TNF‐α, which is essent...

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