H19 regulates angiogenic capacity of extravillous trophoblasts by H19/miR-106a-5p/VEGFA axis

Purpose To investigate the role and underlying mechanism of H19 in regulating angiogenic capacity of extravillous trophoblasts. Methods Gain and loss of function experiments were performed using a human first-trimester extravillous trophoblast (EVT) cell line, HTR-8/SVneo cells. H19 was overexpresse...

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Veröffentlicht in:	Archives of gynecology and obstetrics 2020-03, Vol.301 (3), p.671-679
Hauptverfasser:	Zeng, Hong, He, Dongmei, Xie, Hebin, Zhao, Yuhao, Peng, Zhaoqun, Deng, Huan, Hu, Jinyue, Jiang, Binyuan, Liu, Nenghui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Angiogenesis Cell adhesion & migration Embryos Endocrinology Experiments Female Gene expression Gynecology Human Genetics Humans Maternal-Fetal Medicine Medical research Medicine Medicine & Public Health MicroRNAs - genetics Miscarriage Obstetrics Obstetrics/Perinatology/Midwifery Plasmids Pregnancy Pregnancy Trimester, First RNA, Long Noncoding - genetics Trophoblasts - metabolism Young Adult
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