Design, synthesis and antimycobacterial activity of thiazolidine-2,4-dione-based thiosemicarbazone derivatives

[Display omitted] •The thiosemicarbazone derivatives with thiazolidine-2,4-dione core were designed and synthesized.•The six compounds showed high antimycobacterial activity in vitro with a MIC = 0.031–0.125 µg/ml.•All the tested compounds were characterized by low cytotoxicity in vitro. The two ser...

Ausführliche Beschreibung