Perineural Invasion Reprograms the Immune Microenvironment through Cholinergic Signaling in Pancreatic Ductal Adenocarcinoma

Perineural invasion is a common feature of pancreatic ductal adenocarcinoma (PDAC). Here, we investigated the effect of perineural invasion on the microenvironment and how this affects PDAC progression. Transcriptome expression profiles of PDAC tissues with different perineural invasion status were...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2020-05, Vol.80 (10), p.1991-2003
Hauptverfasser: Yang, Min-Wei, Tao, Ling-Ye, Jiang, Yong-Sheng, Yang, Jian-Yu, Huo, Yan-Miao, Liu, De-Jun, Li, Jiao, Fu, Xue-Liang, He, Ruizhe, Lin, Chaoyi, Liu, Wei, Zhang, Jun-Feng, Hua, Rong, Li, Qing, Jiang, Shu-Heng, Hu, Li-Peng, Tian, Guang-Ang, Zhang, Xiao-Xin, Niu, Ningning, Lu, Ping, Shi, Juanjuan, Xiao, Gary G, Wang, Li-Wei, Xue, Jing, Zhang, Zhi-Gang, Sun, Yong-Wei
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Sprache:eng
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