Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of Checkpoint Kinase 1 via Activating Mammalian Target of Rapamycin C1/Ribosomal Protein S6 Kinase b-1 Pathway

In mammals, regenerative therapy after myocardial infarction is hampered by the limited regenerative capacity of adult heart, whereas a transient regenerative capacity is maintained in the neonatal heart. Systemic phosphorylation signaling analysis on ischemic neonatal myocardium might be helpful to...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 2020-05, Vol.141 (19), p.1554-1569
Hauptverfasser: Fan, Yi, Cheng, Yiwei, Li, Yafei, Chen, Bingrui, Wang, Zimu, Wei, Tianwen, Zhang, Hao, Guo, Yueshuai, Wang, Qiming, Wei, Yongyue, Chen, Feng, Sha, Jiahao, Guo, Xuejiang, Wang, Liansheng
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Sprache:eng
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