Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis
Purpose To estimate the prevalence of degenerative lumbar spinal stenosis (LSS) in adults, identified by clinical symptoms and/or radiological criteria. Methods Systematic review of the literature. Pooled prevalence estimates by care setting and clinical or radiological diagnostic criteria were calc...
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Veröffentlicht in: | European spine journal 2020-09, Vol.29 (9), p.2143-2163 |
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creator | Jensen, Rikke Krüger Jensen, Tue Secher Koes, Bart Hartvigsen, Jan |
description | Purpose
To estimate the prevalence of degenerative lumbar spinal stenosis (LSS) in adults, identified by clinical symptoms and/or radiological criteria.
Methods
Systematic review of the literature. Pooled prevalence estimates by care setting and clinical or radiological diagnostic criteria were calculated and plotted [PROSPERO ID: CRD42018109640].
Results
In total, 41 papers reporting on 55 study samples were included. The overall risk of bias was considered high in two-thirds of the papers. The mean prevalence, based on a clinical diagnosis of LSS in the general population, was 11% (95% CI 4–18%), 25% (95% CI 19–32%) in patients from primary care, 29% (95% CI 22–36%) in patients from secondary care and 39% (95% CI 39–39%) in patients from mixed primary and secondary care. Evaluating the presence of LSS based on radiological diagnosis, the pooled prevalence was 11% (95% CI 5–18%) in the asymptomatic population, 38% (95% CI − 10 to 85%) in the general population, 15% (95% CI 13–18%) in patients from primary care, 32% (95% CI 22–41%) in patients from secondary care and 21% (95% CI 16–26%) in a mixed population from primary and secondary care.
Conclusions
The mean prevalence estimates based on clinical diagnoses vary between 11 and 39%, and the estimates based on radiological diagnoses similarly vary between 11 and 38%. The results are based on studies with high risk of bias, and the pooled prevalence estimates should therefore be interpreted with caution. With an growing elderly population, there is a need for future low risk-of-bias research clarifying clinical and radiological diagnostic criteria of lumbar spinal stenosis.
Graphic abstract
These slides can be retrieved under Electronic Supplementary Material. |
doi_str_mv | 10.1007/s00586-020-06339-1 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2364047487</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2441670046</sourcerecordid><originalsourceid>FETCH-LOGICAL-c419t-8169060af4b3ce95ff311b4cb2a7f669737889cecbe7a06cb68790bd90f885073</originalsourceid><addsrcrecordid>eNp9kU1vFSEUhkmjaa_VP-DCkLhxQ3sYuHy4M40fTZrUha4Jwz3T0MzACDM299-X9lZNXHQFB57zcMJLyFsOZxxAn1eArVEMOmCghLCMH5ENl6JjYEX3gmzASmBKc3tCXtV6C8C3FtQxOREd2LY1G5K_F_ztR0wBaR7ouE69L7TOMfmR1gVTrrHSmOgNJiztzKcdDWNMMbRizvM6-iXmVD9ST-u-dUytDrRZI9490hMunvnm2zfVa_Jy8GPFN0_rKfn55fOPi2_s6vrr5cWnKxYktwszXLVJwQ-yFwHtdhgE570Mfef1oJTVQhtjA4YetQcVemW0hX5nYTBmC1qckg8H71zyrxXr4qZYA46jT5jX6jqhJEgtzQP6_j_0Nq-lzdsoKbnSAFI1qjtQoeRaCw5uLnHyZe84uIc43CEO1-Jwj3E43prePanXfsLd35Y__98AcQBqu0o3WP69_Yz2Hk6alhU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2441670046</pqid></control><display><type>article</type><title>Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis</title><source>Springer Nature - Complete Springer Journals</source><creator>Jensen, Rikke Krüger ; Jensen, Tue Secher ; Koes, Bart ; Hartvigsen, Jan</creator><creatorcontrib>Jensen, Rikke Krüger ; Jensen, Tue Secher ; Koes, Bart ; Hartvigsen, Jan</creatorcontrib><description>Purpose
To estimate the prevalence of degenerative lumbar spinal stenosis (LSS) in adults, identified by clinical symptoms and/or radiological criteria.
Methods
Systematic review of the literature. Pooled prevalence estimates by care setting and clinical or radiological diagnostic criteria were calculated and plotted [PROSPERO ID: CRD42018109640].
Results
In total, 41 papers reporting on 55 study samples were included. The overall risk of bias was considered high in two-thirds of the papers. The mean prevalence, based on a clinical diagnosis of LSS in the general population, was 11% (95% CI 4–18%), 25% (95% CI 19–32%) in patients from primary care, 29% (95% CI 22–36%) in patients from secondary care and 39% (95% CI 39–39%) in patients from mixed primary and secondary care. Evaluating the presence of LSS based on radiological diagnosis, the pooled prevalence was 11% (95% CI 5–18%) in the asymptomatic population, 38% (95% CI − 10 to 85%) in the general population, 15% (95% CI 13–18%) in patients from primary care, 32% (95% CI 22–41%) in patients from secondary care and 21% (95% CI 16–26%) in a mixed population from primary and secondary care.
Conclusions
The mean prevalence estimates based on clinical diagnoses vary between 11 and 39%, and the estimates based on radiological diagnoses similarly vary between 11 and 38%. The results are based on studies with high risk of bias, and the pooled prevalence estimates should therefore be interpreted with caution. With an growing elderly population, there is a need for future low risk-of-bias research clarifying clinical and radiological diagnostic criteria of lumbar spinal stenosis.
Graphic abstract
These slides can be retrieved under Electronic Supplementary Material.</description><identifier>ISSN: 0940-6719</identifier><identifier>EISSN: 1432-0932</identifier><identifier>DOI: 10.1007/s00586-020-06339-1</identifier><identifier>PMID: 32095908</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Bias ; Diagnosis ; Estimates ; Literature reviews ; Medicine ; Medicine & Public Health ; Meta-analysis ; Neurosurgery ; Population ; Primary care ; Review Article ; Spinal stenosis ; Surgical Orthopedics ; Systematic review</subject><ispartof>European spine journal, 2020-09, Vol.29 (9), p.2143-2163</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020</rights><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-8169060af4b3ce95ff311b4cb2a7f669737889cecbe7a06cb68790bd90f885073</citedby><cites>FETCH-LOGICAL-c419t-8169060af4b3ce95ff311b4cb2a7f669737889cecbe7a06cb68790bd90f885073</cites><orcidid>0000-0001-7528-3234</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00586-020-06339-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00586-020-06339-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32095908$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jensen, Rikke Krüger</creatorcontrib><creatorcontrib>Jensen, Tue Secher</creatorcontrib><creatorcontrib>Koes, Bart</creatorcontrib><creatorcontrib>Hartvigsen, Jan</creatorcontrib><title>Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis</title><title>European spine journal</title><addtitle>Eur Spine J</addtitle><addtitle>Eur Spine J</addtitle><description>Purpose
To estimate the prevalence of degenerative lumbar spinal stenosis (LSS) in adults, identified by clinical symptoms and/or radiological criteria.
Methods
Systematic review of the literature. Pooled prevalence estimates by care setting and clinical or radiological diagnostic criteria were calculated and plotted [PROSPERO ID: CRD42018109640].
Results
In total, 41 papers reporting on 55 study samples were included. The overall risk of bias was considered high in two-thirds of the papers. The mean prevalence, based on a clinical diagnosis of LSS in the general population, was 11% (95% CI 4–18%), 25% (95% CI 19–32%) in patients from primary care, 29% (95% CI 22–36%) in patients from secondary care and 39% (95% CI 39–39%) in patients from mixed primary and secondary care. Evaluating the presence of LSS based on radiological diagnosis, the pooled prevalence was 11% (95% CI 5–18%) in the asymptomatic population, 38% (95% CI − 10 to 85%) in the general population, 15% (95% CI 13–18%) in patients from primary care, 32% (95% CI 22–41%) in patients from secondary care and 21% (95% CI 16–26%) in a mixed population from primary and secondary care.
Conclusions
The mean prevalence estimates based on clinical diagnoses vary between 11 and 39%, and the estimates based on radiological diagnoses similarly vary between 11 and 38%. The results are based on studies with high risk of bias, and the pooled prevalence estimates should therefore be interpreted with caution. With an growing elderly population, there is a need for future low risk-of-bias research clarifying clinical and radiological diagnostic criteria of lumbar spinal stenosis.
Graphic abstract
These slides can be retrieved under Electronic Supplementary Material.</description><subject>Bias</subject><subject>Diagnosis</subject><subject>Estimates</subject><subject>Literature reviews</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Meta-analysis</subject><subject>Neurosurgery</subject><subject>Population</subject><subject>Primary care</subject><subject>Review Article</subject><subject>Spinal stenosis</subject><subject>Surgical Orthopedics</subject><subject>Systematic review</subject><issn>0940-6719</issn><issn>1432-0932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kU1vFSEUhkmjaa_VP-DCkLhxQ3sYuHy4M40fTZrUha4Jwz3T0MzACDM299-X9lZNXHQFB57zcMJLyFsOZxxAn1eArVEMOmCghLCMH5ENl6JjYEX3gmzASmBKc3tCXtV6C8C3FtQxOREd2LY1G5K_F_ztR0wBaR7ouE69L7TOMfmR1gVTrrHSmOgNJiztzKcdDWNMMbRizvM6-iXmVD9ST-u-dUytDrRZI9490hMunvnm2zfVa_Jy8GPFN0_rKfn55fOPi2_s6vrr5cWnKxYktwszXLVJwQ-yFwHtdhgE570Mfef1oJTVQhtjA4YetQcVemW0hX5nYTBmC1qckg8H71zyrxXr4qZYA46jT5jX6jqhJEgtzQP6_j_0Nq-lzdsoKbnSAFI1qjtQoeRaCw5uLnHyZe84uIc43CEO1-Jwj3E43prePanXfsLd35Y__98AcQBqu0o3WP69_Yz2Hk6alhU</recordid><startdate>20200901</startdate><enddate>20200901</enddate><creator>Jensen, Rikke Krüger</creator><creator>Jensen, Tue Secher</creator><creator>Koes, Bart</creator><creator>Hartvigsen, Jan</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7528-3234</orcidid></search><sort><creationdate>20200901</creationdate><title>Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis</title><author>Jensen, Rikke Krüger ; Jensen, Tue Secher ; Koes, Bart ; Hartvigsen, Jan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-8169060af4b3ce95ff311b4cb2a7f669737889cecbe7a06cb68790bd90f885073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Bias</topic><topic>Diagnosis</topic><topic>Estimates</topic><topic>Literature reviews</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Meta-analysis</topic><topic>Neurosurgery</topic><topic>Population</topic><topic>Primary care</topic><topic>Review Article</topic><topic>Spinal stenosis</topic><topic>Surgical Orthopedics</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jensen, Rikke Krüger</creatorcontrib><creatorcontrib>Jensen, Tue Secher</creatorcontrib><creatorcontrib>Koes, Bart</creatorcontrib><creatorcontrib>Hartvigsen, Jan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European spine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jensen, Rikke Krüger</au><au>Jensen, Tue Secher</au><au>Koes, Bart</au><au>Hartvigsen, Jan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis</atitle><jtitle>European spine journal</jtitle><stitle>Eur Spine J</stitle><addtitle>Eur Spine J</addtitle><date>2020-09-01</date><risdate>2020</risdate><volume>29</volume><issue>9</issue><spage>2143</spage><epage>2163</epage><pages>2143-2163</pages><issn>0940-6719</issn><eissn>1432-0932</eissn><abstract>Purpose
To estimate the prevalence of degenerative lumbar spinal stenosis (LSS) in adults, identified by clinical symptoms and/or radiological criteria.
Methods
Systematic review of the literature. Pooled prevalence estimates by care setting and clinical or radiological diagnostic criteria were calculated and plotted [PROSPERO ID: CRD42018109640].
Results
In total, 41 papers reporting on 55 study samples were included. The overall risk of bias was considered high in two-thirds of the papers. The mean prevalence, based on a clinical diagnosis of LSS in the general population, was 11% (95% CI 4–18%), 25% (95% CI 19–32%) in patients from primary care, 29% (95% CI 22–36%) in patients from secondary care and 39% (95% CI 39–39%) in patients from mixed primary and secondary care. Evaluating the presence of LSS based on radiological diagnosis, the pooled prevalence was 11% (95% CI 5–18%) in the asymptomatic population, 38% (95% CI − 10 to 85%) in the general population, 15% (95% CI 13–18%) in patients from primary care, 32% (95% CI 22–41%) in patients from secondary care and 21% (95% CI 16–26%) in a mixed population from primary and secondary care.
Conclusions
The mean prevalence estimates based on clinical diagnoses vary between 11 and 39%, and the estimates based on radiological diagnoses similarly vary between 11 and 38%. The results are based on studies with high risk of bias, and the pooled prevalence estimates should therefore be interpreted with caution. With an growing elderly population, there is a need for future low risk-of-bias research clarifying clinical and radiological diagnostic criteria of lumbar spinal stenosis.
Graphic abstract
These slides can be retrieved under Electronic Supplementary Material.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32095908</pmid><doi>10.1007/s00586-020-06339-1</doi><tpages>21</tpages><orcidid>https://orcid.org/0000-0001-7528-3234</orcidid><oa>free_for_read</oa></addata></record> |
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source | Springer Nature - Complete Springer Journals |
subjects | Bias Diagnosis Estimates Literature reviews Medicine Medicine & Public Health Meta-analysis Neurosurgery Population Primary care Review Article Spinal stenosis Surgical Orthopedics Systematic review |
title | Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis |
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