Effects of epidural combined with general anesthesia versus general anesthesia on quality of recovery of elderly patients undergoing laparoscopic radical resection of colorectal cancer: A prospective randomized trial
The aim of the present study was to assess the quality of recovery from anesthesia on patients subjected to laparoscopic radical resection of colorectal cancer under epidural block combined with general anesthesia or general anesthesia by means of Quality of Recovery-15 (QoR-15) questionnaire. Prosp...
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| Veröffentlicht in: | Journal of clinical anesthesia 2020-06, Vol.62, p.109742-109742, Article 109742 |
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| creator | Liu, Qin Lin, Jing-yan Zhang, Yun-feng Zhu, Na Wang, Guo-qiang Wang, Shun Gao, Peng-fei |
| description | The aim of the present study was to assess the quality of recovery from anesthesia on patients subjected to laparoscopic radical resection of colorectal cancer under epidural block combined with general anesthesia or general anesthesia by means of Quality of Recovery-15 (QoR-15) questionnaire.
Prospective randomized trial.
The setting is at an operating room, a post-anesthesia care unit, and a hospital ward.
Seventy patients, aging from 65 to 79 years with an American Society of Anesthesiologists physical status II or III, were scheduled to undergo laparoscopic radical resection of colorectal cancer.
Epidural block combined with general anesthesia or general anesthesia.
The QoR-15 was administered by an investigator blind to group allocation before surgery (T0), at 24 and 72h after surgery (T1 and T2), and on postoperative day 7 (T3). The quality of recovery, as assessed by the score on the QoR-15, was compared between the groups. Besides, the consumption of anesthetics, respiratory recovery time, response time, extubation time, flatus time, the incidence of nausea or vomiting, the consumption of antiemetic and analgesic agents, and the duration of the hospital stay were also recorded.
The QoR-15 scores at T1 and T2 were significantly higher in the E + G group compared with the G group (P |
| doi_str_mv | 10.1016/j.jclinane.2020.109742 |
| format | Article |
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Prospective randomized trial.
The setting is at an operating room, a post-anesthesia care unit, and a hospital ward.
Seventy patients, aging from 65 to 79 years with an American Society of Anesthesiologists physical status II or III, were scheduled to undergo laparoscopic radical resection of colorectal cancer.
Epidural block combined with general anesthesia or general anesthesia.
The QoR-15 was administered by an investigator blind to group allocation before surgery (T0), at 24 and 72h after surgery (T1 and T2), and on postoperative day 7 (T3). The quality of recovery, as assessed by the score on the QoR-15, was compared between the groups. Besides, the consumption of anesthetics, respiratory recovery time, response time, extubation time, flatus time, the incidence of nausea or vomiting, the consumption of antiemetic and analgesic agents, and the duration of the hospital stay were also recorded.
The QoR-15 scores at T1 and T2 were significantly higher in the E + G group compared with the G group (P < 0.05). Among the five dimensions of the QoR-15, physiological comfort, physiological independence, pain, and emotional dimension were significantly better at T1 in the E + G group, and physiological comfort and pain were significantly better at T2 in the E + G group.
This study demonstrates that epidural block combined with general anesthesia can improve the early recovery of elderly patients after laparoscopic radical resection of colorectal cancer from the perspective of patients.</description><identifier>ISSN: 0952-8180</identifier><identifier>EISSN: 1873-4529</identifier><identifier>DOI: 10.1016/j.jclinane.2020.109742</identifier><identifier>PMID: 32088534</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anesthesia ; Catheters ; Colorectal cancer ; Colorectal surgery ; Consciousness ; Epidural ; Fentanyl ; General anesthesia ; Hospitals ; Laparoscopy ; Medical personnel ; Pain ; Patients ; Postoperative ; QoR-15 ; Quality ; Questionnaires ; Recovery ; Recovery (Medical) ; Respiration</subject><ispartof>Journal of clinical anesthesia, 2020-06, Vol.62, p.109742-109742, Article 109742</ispartof><rights>2020 Elsevier Inc.</rights><rights>Copyright © 2020 Elsevier Inc. All rights reserved.</rights><rights>2020. Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-d8dfc1f46afe8a06f33b0900eda34e0f7e4d4077eb583b15f4ec4d270031b2763</citedby><cites>FETCH-LOGICAL-c396t-d8dfc1f46afe8a06f33b0900eda34e0f7e4d4077eb583b15f4ec4d270031b2763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2425680868?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32088534$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Qin</creatorcontrib><creatorcontrib>Lin, Jing-yan</creatorcontrib><creatorcontrib>Zhang, Yun-feng</creatorcontrib><creatorcontrib>Zhu, Na</creatorcontrib><creatorcontrib>Wang, Guo-qiang</creatorcontrib><creatorcontrib>Wang, Shun</creatorcontrib><creatorcontrib>Gao, Peng-fei</creatorcontrib><title>Effects of epidural combined with general anesthesia versus general anesthesia on quality of recovery of elderly patients undergoing laparoscopic radical resection of colorectal cancer: A prospective randomized trial</title><title>Journal of clinical anesthesia</title><addtitle>J Clin Anesth</addtitle><description>The aim of the present study was to assess the quality of recovery from anesthesia on patients subjected to laparoscopic radical resection of colorectal cancer under epidural block combined with general anesthesia or general anesthesia by means of Quality of Recovery-15 (QoR-15) questionnaire.
Prospective randomized trial.
The setting is at an operating room, a post-anesthesia care unit, and a hospital ward.
Seventy patients, aging from 65 to 79 years with an American Society of Anesthesiologists physical status II or III, were scheduled to undergo laparoscopic radical resection of colorectal cancer.
Epidural block combined with general anesthesia or general anesthesia.
The QoR-15 was administered by an investigator blind to group allocation before surgery (T0), at 24 and 72h after surgery (T1 and T2), and on postoperative day 7 (T3). The quality of recovery, as assessed by the score on the QoR-15, was compared between the groups. Besides, the consumption of anesthetics, respiratory recovery time, response time, extubation time, flatus time, the incidence of nausea or vomiting, the consumption of antiemetic and analgesic agents, and the duration of the hospital stay were also recorded.
The QoR-15 scores at T1 and T2 were significantly higher in the E + G group compared with the G group (P < 0.05). Among the five dimensions of the QoR-15, physiological comfort, physiological independence, pain, and emotional dimension were significantly better at T1 in the E + G group, and physiological comfort and pain were significantly better at T2 in the E + G group.
This study demonstrates that epidural block combined with general anesthesia can improve the early recovery of elderly patients after laparoscopic radical resection of colorectal cancer from the perspective of patients.</description><subject>Anesthesia</subject><subject>Catheters</subject><subject>Colorectal cancer</subject><subject>Colorectal surgery</subject><subject>Consciousness</subject><subject>Epidural</subject><subject>Fentanyl</subject><subject>General anesthesia</subject><subject>Hospitals</subject><subject>Laparoscopy</subject><subject>Medical personnel</subject><subject>Pain</subject><subject>Patients</subject><subject>Postoperative</subject><subject>QoR-15</subject><subject>Quality</subject><subject>Questionnaires</subject><subject>Recovery</subject><subject>Recovery (Medical)</subject><subject>Respiration</subject><issn>0952-8180</issn><issn>1873-4529</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFUU1v1DAUjBCIbgt_obLEhcsujp0PhxNVVQpSJS5wthz7eevIsVM7WbT8Un4OL2zLASFxsvU8M288UxSXJd2VtGzeDbtBexdUgB2jbB12bcWeFZtStHxb1ax7XmxoV7OtKAU9K85zHiil-FC-LM44o0LUvNoUP2-sBT1nEi2ByZklKU90HHsXwJDvbr4newiwTnFXnu8hO0UOkPKS__USA3lYlHfzcVVMoCNif9_BG0j-SCY1Owi4cQk42EcX9sSrSaWYdZycJkkZp1E1QUZnDhWRraOPqDav7lTQkN6TKzIhZ1oxB0BWMHF0P9D1nJzyr4oXVvkMrx_Pi-Lbx5uv15-2d19uP19f3W0175p5a4SxurRVoywIRRvLeU87SsEoXgG1LVSmom0LfS14X9a2Al0Z1lLKy561Db8o3p500czDgjnI0WUN3mMoccmS8YZj2LytEfrmL-gQlxTQnWQVqxtBRSMQ1ZxQGn-XE1g5JTeqdJQllWv3cpBP3cu1e3nqHomXj_JLP4L5Q3sqGwEfTgDAPA4Okswaq9Bg3BqtNNH9b8cvt8vJ3g</recordid><startdate>202006</startdate><enddate>202006</enddate><creator>Liu, Qin</creator><creator>Lin, Jing-yan</creator><creator>Zhang, Yun-feng</creator><creator>Zhu, Na</creator><creator>Wang, Guo-qiang</creator><creator>Wang, Shun</creator><creator>Gao, Peng-fei</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>202006</creationdate><title>Effects of epidural combined with general anesthesia versus general anesthesia on quality of recovery of elderly patients undergoing laparoscopic radical resection of colorectal cancer: A prospective randomized trial</title><author>Liu, Qin ; Lin, Jing-yan ; Zhang, Yun-feng ; Zhu, Na ; Wang, Guo-qiang ; Wang, Shun ; Gao, Peng-fei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-d8dfc1f46afe8a06f33b0900eda34e0f7e4d4077eb583b15f4ec4d270031b2763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Anesthesia</topic><topic>Catheters</topic><topic>Colorectal cancer</topic><topic>Colorectal surgery</topic><topic>Consciousness</topic><topic>Epidural</topic><topic>Fentanyl</topic><topic>General anesthesia</topic><topic>Hospitals</topic><topic>Laparoscopy</topic><topic>Medical personnel</topic><topic>Pain</topic><topic>Patients</topic><topic>Postoperative</topic><topic>QoR-15</topic><topic>Quality</topic><topic>Questionnaires</topic><topic>Recovery</topic><topic>Recovery (Medical)</topic><topic>Respiration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Qin</creatorcontrib><creatorcontrib>Lin, Jing-yan</creatorcontrib><creatorcontrib>Zhang, Yun-feng</creatorcontrib><creatorcontrib>Zhu, Na</creatorcontrib><creatorcontrib>Wang, Guo-qiang</creatorcontrib><creatorcontrib>Wang, Shun</creatorcontrib><creatorcontrib>Gao, Peng-fei</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Qin</au><au>Lin, Jing-yan</au><au>Zhang, Yun-feng</au><au>Zhu, Na</au><au>Wang, Guo-qiang</au><au>Wang, Shun</au><au>Gao, Peng-fei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of epidural combined with general anesthesia versus general anesthesia on quality of recovery of elderly patients undergoing laparoscopic radical resection of colorectal cancer: A prospective randomized trial</atitle><jtitle>Journal of clinical anesthesia</jtitle><addtitle>J Clin Anesth</addtitle><date>2020-06</date><risdate>2020</risdate><volume>62</volume><spage>109742</spage><epage>109742</epage><pages>109742-109742</pages><artnum>109742</artnum><issn>0952-8180</issn><eissn>1873-4529</eissn><abstract>The aim of the present study was to assess the quality of recovery from anesthesia on patients subjected to laparoscopic radical resection of colorectal cancer under epidural block combined with general anesthesia or general anesthesia by means of Quality of Recovery-15 (QoR-15) questionnaire.
Prospective randomized trial.
The setting is at an operating room, a post-anesthesia care unit, and a hospital ward.
Seventy patients, aging from 65 to 79 years with an American Society of Anesthesiologists physical status II or III, were scheduled to undergo laparoscopic radical resection of colorectal cancer.
Epidural block combined with general anesthesia or general anesthesia.
The QoR-15 was administered by an investigator blind to group allocation before surgery (T0), at 24 and 72h after surgery (T1 and T2), and on postoperative day 7 (T3). The quality of recovery, as assessed by the score on the QoR-15, was compared between the groups. Besides, the consumption of anesthetics, respiratory recovery time, response time, extubation time, flatus time, the incidence of nausea or vomiting, the consumption of antiemetic and analgesic agents, and the duration of the hospital stay were also recorded.
The QoR-15 scores at T1 and T2 were significantly higher in the E + G group compared with the G group (P < 0.05). Among the five dimensions of the QoR-15, physiological comfort, physiological independence, pain, and emotional dimension were significantly better at T1 in the E + G group, and physiological comfort and pain were significantly better at T2 in the E + G group.
This study demonstrates that epidural block combined with general anesthesia can improve the early recovery of elderly patients after laparoscopic radical resection of colorectal cancer from the perspective of patients.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>32088534</pmid><doi>10.1016/j.jclinane.2020.109742</doi><tpages>1</tpages></addata></record> |
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| subjects | Anesthesia Catheters Colorectal cancer Colorectal surgery Consciousness Epidural Fentanyl General anesthesia Hospitals Laparoscopy Medical personnel Pain Patients Postoperative QoR-15 Quality Questionnaires Recovery Recovery (Medical) Respiration |
| title | Effects of epidural combined with general anesthesia versus general anesthesia on quality of recovery of elderly patients undergoing laparoscopic radical resection of colorectal cancer: A prospective randomized trial |
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