Your results may vary: the imprecision of medical measurements
[...]most importantly, there is biological variation. Biological variation comes about through the convergence of the innumerable perturbations of our physiology, state of health, living environment, diet, activity, stress, mood, the weather and climate, and environmental exposures. The first data c...
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| Veröffentlicht in: | BMJ (Online) 2020-02, Vol.368, p.m149-m149 |
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| container_title | BMJ (Online) |
| container_volume | 368 |
| creator | McCormack, James P Holmes, Daniel T |
| description | [...]most importantly, there is biological variation. Biological variation comes about through the convergence of the innumerable perturbations of our physiology, state of health, living environment, diet, activity, stress, mood, the weather and climate, and environmental exposures. The first data column of the table conveys the actual analytical confidence interval or error due to the measurement process alone, without any consideration of biological effects. [...]if a significance level larger than 0.05 is chosen, the required change will be smaller (see appendix). |
| doi_str_mv | 10.1136/bmj.m149 |
| format | Article |
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| subjects | Adaptor Proteins, Vesicular Transport - blood Biological variation Biomarkers - metabolism Bone Density - drug effects Bone Density Conservation Agents - pharmacology Cholesterol Clinical decision making Clinical Laboratory Techniques - standards Confidence intervals Decision making Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - diagnosis Diagnostic Errors Diagnostic Tests, Routine - standards Diphosphonates - pharmacology Drug Monitoring - methods Estimates Glycated Hemoglobin A - metabolism Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Laboratories Metabolites Patients Physiology Reproducibility of Results Statistical analysis Uncertainty Variation Vitamin D |
| title | Your results may vary: the imprecision of medical measurements |
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