Prenatal alcohol exposure and developmental programming of mental illness
It is well established that high-dose alcohol consumption during pregnancy increases the risk for a plethora of adverse offspring outcomes. These include neurodevelopmental, cognitive and social deficits, as well as psychiatric illnesses, such as depression and anxiety. However, much less evidence i...
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Veröffentlicht in: | Journal of developmental origins of health and disease 2020-06, Vol.11 (3), p.211-221 |
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description | It is well established that high-dose alcohol consumption during pregnancy increases the risk for a plethora of adverse offspring outcomes. These include neurodevelopmental, cognitive and social deficits, as well as psychiatric illnesses, such as depression and anxiety. However, much less evidence is available on the effects of low- and early-dose alcohol exposure on mental health outcomes, regardless of the accumulating evidence that mental health outcomes should be considered in the context of the Developmental Origins of Health and Disease hypothesis. This review will discuss the evidence that indicates low-dose and early prenatal alcohol exposure can increase the risk of mental illness in offspring and discuss the mechanistic pathways that may be involved. |
doi_str_mv | 10.1017/S2040174420000082 |
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These include neurodevelopmental, cognitive and social deficits, as well as psychiatric illnesses, such as depression and anxiety. However, much less evidence is available on the effects of low- and early-dose alcohol exposure on mental health outcomes, regardless of the accumulating evidence that mental health outcomes should be considered in the context of the Developmental Origins of Health and Disease hypothesis. This review will discuss the evidence that indicates low-dose and early prenatal alcohol exposure can increase the risk of mental illness in offspring and discuss the mechanistic pathways that may be involved.</description><identifier>ISSN: 2040-1744</identifier><identifier>EISSN: 2040-1752</identifier><identifier>DOI: 10.1017/S2040174420000082</identifier><identifier>PMID: 32077395</identifier><language>eng</language><publisher>England: Cambridge University Press</publisher><subject>Alcohol ; Anxiety ; Autism ; Behavior ; Birth weight ; Drug use ; Emotional disorders ; Executive function ; Hyperactivity ; Hypotheses ; Hypoxia ; Mental depression ; Mental disorders ; Mental health care ; Metabolism ; Mood disorders ; Pregnancy ; Psychosis ; Schizophrenia ; Stress ; Studies</subject><ispartof>Journal of developmental origins of health and disease, 2020-06, Vol.11 (3), p.211-221</ispartof><rights>The Author(s) 2020. 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subjects | Alcohol Anxiety Autism Behavior Birth weight Drug use Emotional disorders Executive function Hyperactivity Hypotheses Hypoxia Mental depression Mental disorders Mental health care Metabolism Mood disorders Pregnancy Psychosis Schizophrenia Stress Studies |
title | Prenatal alcohol exposure and developmental programming of mental illness |
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