Prenatal alcohol exposure and developmental programming of mental illness

It is well established that high-dose alcohol consumption during pregnancy increases the risk for a plethora of adverse offspring outcomes. These include neurodevelopmental, cognitive and social deficits, as well as psychiatric illnesses, such as depression and anxiety. However, much less evidence i...

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Veröffentlicht in:Journal of developmental origins of health and disease 2020-06, Vol.11 (3), p.211-221
Hauptverfasser: Burgess, Danielle J, Moritz, Karen M
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container_title Journal of developmental origins of health and disease
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creator Burgess, Danielle J
Moritz, Karen M
description It is well established that high-dose alcohol consumption during pregnancy increases the risk for a plethora of adverse offspring outcomes. These include neurodevelopmental, cognitive and social deficits, as well as psychiatric illnesses, such as depression and anxiety. However, much less evidence is available on the effects of low- and early-dose alcohol exposure on mental health outcomes, regardless of the accumulating evidence that mental health outcomes should be considered in the context of the Developmental Origins of Health and Disease hypothesis. This review will discuss the evidence that indicates low-dose and early prenatal alcohol exposure can increase the risk of mental illness in offspring and discuss the mechanistic pathways that may be involved.
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subjects Alcohol
Anxiety
Autism
Behavior
Birth weight
Drug use
Emotional disorders
Executive function
Hyperactivity
Hypotheses
Hypoxia
Mental depression
Mental disorders
Mental health care
Metabolism
Mood disorders
Pregnancy
Psychosis
Schizophrenia
Stress
Studies
title Prenatal alcohol exposure and developmental programming of mental illness
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