Results of a Randomized Phase IIb Trial of Nelipepimut-S + Trastuzumab versus Trastuzumab to Prevent Recurrences in Patients with High-Risk HER2 Low-Expressing Breast Cancer

Preclinical data provide evidence for synergism between HER2-targeted peptide vaccines and trastuzumab. The efficacy of this combination was evaluated in patients with HER2 low-expressing breast cancer in the adjuvant setting. A phase IIb, multicenter, randomized, single-blinded, controlled trial en...

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Veröffentlicht in:Clinical cancer research 2020-06, Vol.26 (11), p.2515-2523
Hauptverfasser: Clifton, G Travis, Hale, Diane, Vreeland, Timothy J, Hickerson, Annelies T, Litton, Jennifer K, Alatrash, Gheath, Murthy, Rashmi K, Qiao, Na, Philips, Anne V, Lukas, Jason J, Holmes, Jarrod P, Peoples, George E, Mittendorf, Elizabeth A
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Sprache:eng
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