Fluoxetine exposure for more than 2 days decreases the neuronal plasticity mediated by CRMP2 in differentiated PC12 cells

•FLU exposure increased neuronal plasticity at day 1.•FLU exposure for longer periods has an opposite effect on the regulation of neuronal plasticity at day 1 and day 3.•The regulation of CRMP2 activity influenced the neuronal plasticity. Recent studies indicate that antidepressants treatment restor...

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Veröffentlicht in:	Brain research bulletin 2020-05, Vol.158, p.99-107
Hauptverfasser:	Wu, Zuotian, Wang, Gaohua, Wang, Huiling, Xiao, Ling, Wei, Yanyan, Yang, Can
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressant CRMP2 Depression Fluoxetine Plasticity
Online-Zugang:	Volltext
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