Desymmetrization of C2‐Symmetric Bis(Boronic Esters) by Zweifel Olefinations

anti‐Configured 1,3‐dimethyl deoxypropionate motifs are important sub structures in natural products. Herein, we describe a bidirectional approach for the rapid construction of natural products featuring such motifs by using C2‐symmetrical 1,3‐bis(boronic esters). As for its application in convergen...

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Veröffentlicht in:	Chemistry : a European journal 2020-06, Vol.26 (36), p.7998-8002
Hauptverfasser:	Linne, Yannick, Schönwald, Axel, Weißbach, Sebastian, Kalesse, Markus
Format:	Artikel
Sprache:	eng
Schlagworte:	C2-symmetry Chemistry desymmetrization Esters lithiation–borylation chemistry mono-Zweifel olefination natural product synthesis Natural products Nucleophiles
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