Toward Genetic Prediction of Nonalcoholic Fatty Liver Disease Trajectories: PNPLA3 and Beyond

Nonalcoholic fatty liver disease (NAFLD) is on the verge of becoming the leading cause of liver disease. NAFLD develops at the interface between environmental factors and inherited predisposition. Genome-wide association studies, followed by exome-wide analyses, led to identification of genetic risk...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2020-05, Vol.158 (7), p.1865-1880.e1
Hauptverfasser:	Krawczyk, Marcin, Liebe, Roman, Lammert, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponutrin Animals Genetic Predisposition to Disease Genetic Risk Score Genetic Variation Genome-Wide Association Study Genomics Humans Lipase - genetics Membrane Proteins - genetics Non-alcoholic Fatty Liver Disease - diagnosis Non-alcoholic Fatty Liver Disease - genetics Nonalcoholic Steatohepatitis Phenotype Risk Assessment Risk Factor Risk Factors Risk Prediction
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