DNA copy number changes correlate with clinical behavior in melanocytic neoplasms: proposal of an algorithmic approach

Increasingly, molecular methods are being utilized in the workup of melanocytic neoplasms. To this end, we sought to correlate data from a single nucleotide polymorphism (SNP) array platform based on molecular inversion probes with clinical data. Copy number variation (CNV) data were obtained on 95...

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Veröffentlicht in:	Modern pathology 2020-07, Vol.33 (7), p.1307-1317
Hauptverfasser:	Alomari, Ahmed K., Miedema, Jayson R., Carter, Michael D., Harms, Paul W., Lowe, Lori, Durham, Alison B., Fullen, Douglas R., Patel, Rajiv M., Hristov, Alexandra C., Chan, May P., Wang, Min, Andea, Aleodor A.
Format:	Artikel
Sprache:	eng
Schlagworte:	38/32 45 45/61 631/67/1813/1634 692/699/67/1813/1634 692/699/67/68 Adolescent Adult Adverse events Aged Aged, 80 and over Algorithms Biomarkers, Tumor - genetics Child Child, Preschool Copy number DNA Copy Number Variations - genetics DNA probes Female Humans Infant Laboratory Medicine Male Medicine Medicine & Public Health Melanoma Melanoma - genetics Melanoma - pathology Middle Aged Nevus, Pigmented - genetics Nevus, Pigmented - pathology Pathology Polymorphism, Single Nucleotide - genetics Single-nucleotide polymorphism Skin Neoplasms - genetics Skin Neoplasms - pathology Statistical analysis Tumors Young Adult
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