Engineering bacterial symbionts of nematodes improves their biocontrol potential to counter the western corn rootworm

The western corn rootworm (WCR) decimates maize crops worldwide. One potential way to control this pest is treatment with entomopathogenic nematodes (EPNs) that harbor bacterial symbionts that are pathogenic to insects. However, WCR larvae sequester benzoxazinoid secondary metabolites that are produ...

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Veröffentlicht in:	Nature biotechnology 2020-05, Vol.38 (5), p.600-608
Hauptverfasser:	Machado, Ricardo A. R., Thönen, Lisa, Arce, Carla C. M., Theepan, Vanitha, Prada, Fausto, Wüthrich, Daniel, Robert, Christelle A. M., Vogiatzaki, Evangelia, Shi, Yi-Ming, Schaeren, Olivier P., Notter, Matheus, Bruggmann, Rémy, Hapfelmeier, Siegfried, Bode, Helge B., Erb, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/2522 631/61 631/92/604 Agricultural pests Agriculture Animals Aquaporins - genetics Aquatic life Bacteria Bacterial Proteins - genetics Benzoxazines - pharmacology Bioinformatics Biological control Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Cereal crops Corn Diabrotica virgifera virgifera Drug Resistance, Bacterial Entomopathogenic nematodes Evolution Evolution, Molecular Genetic Engineering Insects Larvae Life Sciences Metabolites Mutation Nematoda Nematoda - microbiology Nematoda - pathogenicity Nematodes Pest control Pest Control, Biological Pest resistance Pests Photorhabdus Photorhabdus - drug effects Photorhabdus - genetics Photorhabdus - physiology Plant Diseases - prevention & control Plant metabolites Secondary metabolites Sequestering Symbionts Toxins Zea mays - growth & development Zea mays - parasitology
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