Alternative methods to reduce the animal use in quality controls of inactivated BTV8 Bluetongue vaccines

The acceptance of serology data instead of challenge for market release of new batches of commercial vaccine is under evaluation by regulatory agencies in order to reduce the use of animals and costs for manufacturers. In this study two vaccines for Bluetongue virus serotype 8 were submitted to qual...

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Veröffentlicht in:	Preventive veterinary medicine 2020-03, Vol.176, p.104923-104923, Article 104923
Hauptverfasser:	Luciani, Mirella, Di Febo, Tiziana, Ronchi, Gaetano Federico, Sacchini, Flavio, Rossi, Emanuela, Ulisse, Simonetta, Di Pancrazio, Chiara, Antonucci, Daniela, Salini, Romolo, Teodori, Liana, Podaliri Vulpiani, Michele, Tittarelli, Manuela, Di Ventura, Mauro
Format:	Artikel
Sprache:	eng
Schlagworte:	Bluetongue virus serotype 8 Cytokines quantification ELISA Inactivated vaccine Quality controls VP2 quantification
Online-Zugang:	Volltext
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