Primary disruption of the default mode network subsystems in drug-naïve Parkinson’s disease with mild cognitive impairments

Purpose Mild cognitive impairment (MCI) in Parkinson’s disease (PD) is related to the disrupted connectivity in networks involved in cognition, primarily in the default mode network (DMN). The DMN contains a midline core and two distinct subsystems (dorsal medial prefrontal cortex (DMPFC) and medial...

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