Dynamin 2‐dependent endocytosis is essential for mouse oocyte development and fertility

During folliculogenesis, oocytes are dependent on metabolic and molecular support from surrounding somatic cells. Here, we examined the role of the dynamin (DNM) family of mechanoenzymes in mediating endocytotic uptake into growing follicular oocytes. We found DNM1 and DNM2 to be highly expressed in...

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Veröffentlicht in:	The FASEB journal 2020-04, Vol.34 (4), p.5162-5177
Hauptverfasser:	Mihalas, Bettina P., Redgrove, Kate A., Bernstein, Ilana R., Robertson, Mark J., McCluskey, Adam, Nixon, Brett, Holt, Janet E., McLaughlin, Eileen A., Sutherland, Jessie M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals dynamin Dynamin I - physiology Dynamin II - physiology Endocytosis Female Fertility folliculogenesis Male Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic oocyte Oocytes - cytology Oocytes - physiology oogenesis Ovarian Follicle - cytology Ovarian Follicle - physiology
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