The acetyltransferase p300 regulates NRF2 stability and localization

The transcription factor NRF2 plays a key role in the protection against environmental stress and maintaining cellular homeostasis. The acetyltransferase p300 is a known component of the NRF2 transcriptional complex and promotes its transcriptional activity. In this study we describe a novel mechani...

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Veröffentlicht in:	Biochemical and biophysical research communications 2020-04, Vol.524 (4), p.895-902
Hauptverfasser:	Ganner, Athina, Pfeiffer, Zazie-Charlotte, Wingendorf, Laura, Kreis, Saskia, Klein, Marinella, Walz, Gerd, Neumann-Haefelin, Elke
Format:	Artikel
Sprache:	eng
Schlagworte:	NRF2 Nuclear localization Oxidative stress p300 Protein stabilization
Online-Zugang:	Volltext
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