Thioredoxin-2 impacts the inflammatory response via suppression of NF-κB and MAPK signaling in sepsis shock

Sepsis is a progressive disease characterized by excessive inflammatory responses, severe tissue injury and organ dysfunction, ultimately leading to mortality. In this study, we demonstrated that thioredoxin-2 (TRX-2) expression is reduced in macrophages stimulated with lipopolysaccharide (LPS). Ove...

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Veröffentlicht in:	Biochemical and biophysical research communications 2020-04, Vol.524 (4), p.876-882
Hauptverfasser:	Wang, Xi, Xing, Yanyan, Tang, Zhongyan, Tang, Yuedong, Shen, Jie, Zhang, Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Inflammatory MAPK NF-κB Sepsis TRX-2
Online-Zugang:	Volltext
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