Study of Small Intestinal Bacterial Overgrowth in a Cohort of Patients with Abdominal Symptoms Who Underwent Bariatric Surgery

Introduction Small intestinal bacterial overgrowth (SIBO) is a common complication of bariatric surgery. Digestive decontamination treatments with oral antibiotic therapy vary and are not codified. This retrospective study was conducted to analyse the characteristics of bariatric surgery patients wh...

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Veröffentlicht in:Obesity surgery 2020-06, Vol.30 (6), p.2331-2337
Hauptverfasser: Mouillot, Thomas, Rhyman, Nybel, Gauthier, Cyril, Paris, Justine, Lang, Anne-Sophie, Lepers-Tassy, Sarah, Manfredi, Sylvain, Lepage, Côme, Leloup, Corinne, Jacquin-Piques, Agnès, Brindisi, Marie-Claude, Brondel, Laurent
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Sprache:eng
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Zusammenfassung:Introduction Small intestinal bacterial overgrowth (SIBO) is a common complication of bariatric surgery. Digestive decontamination treatments with oral antibiotic therapy vary and are not codified. This retrospective study was conducted to analyse the characteristics of bariatric surgery patients who underwent a glucose breath test (GBT) and to analyse the effectiveness of the antibiotic decontamination therapy. Materials and Methods A total of 101 operated patients (Roux-en-Y bypass (RYB), omega bypass (ΩB) and sleeve gastrectomy (SG)) who underwent a GBT (75 g/250 mL) were included. Anthropometric data, symptoms of SIBO, type of surgery, use of proton pump inhibitors (PPIs) and antibiotic therapy were analysed. The effectiveness of the antibiotic treatment, defined by improvement of the symptoms, was evaluated during the follow-up. Results Of the 85 women and 16 men included (48.5 ± 3.6 years old), 63 underwent RYB, 31 underwent ΩB and 7 underwent SG. The GBT was positive in 83% of the patients. A positive test was associated with age ( p  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-020-04477-5