Chronic Infiltration of T Lymphocytes into the Brain in a Non-human Primate Model of Parkinson’s Disease

•Brains of non-human primates induced by with MPTP showed chronic infiltration of T-cells.•T-cells were observed in close proximity to dopaminergic neurons of the non-human primates Parkinson’s disease model.•DAT expression was found on infiltrated CD4+ and CD8+ T-cells.•Chronic normalization of ser...

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Veröffentlicht in:	Neuroscience 2020-04, Vol.431, p.73-85
Hauptverfasser:	Seo, Jincheol, Park, Junghyung, Kim, Keonwoo, Won, Jinyoung, Yeo, Hyeon-Gu, Jin, Yeung Bae, Koo, Bon-Sang, Lim, Kyung Seob, Jeong, Kang-Jin, Kang, Philyong, Lee, Hwal-Yong, Choi, Won Seok, Baek, Seung Ho, Jeon, Chang-Yeop, Hong, Jung-Joo, Huh, Jae-Won, Kim, Young-Hyun, Park, Sang Je, Kim, Sun-Uk, Lee, Dong-Seok, Lee, Sang-Rae, Lee, Youngjeon
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Animals Brain Disease Models, Animal dopamine transporter Dopaminergic Neurons Mice Mice, Inbred C57BL MPTP non-human primate Parkinson Disease Parkinson’s disease Primates RANTES T-cell
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