Development of a Linker-Mediated Immunoassay Using Chemically Transitioned Nanosensors

Sensitive and specific quantification of protein biomarkers is important in medical diagnostics, academic research, and pharmaceutical development. However, multiple binding steps in conventional sandwich immunoassay protocols result in high assay hands-on-time and delayed results. This is particula...

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Veröffentlicht in:	Analytical chemistry (Washington) 2020-03, Vol.92 (5), p.3627-3635
Hauptverfasser:	Smith, Lucas D, Willard, Michael C, Smith, Jordan P, Cunningham, Brian T
Format:	Artikel
Sprache:	eng
Schlagworte:	Additives Antibodies Antibodies - immunology Antibodies - metabolism Antigens Binding Biomarkers Biosensing Techniques - methods Calcium-binding protein Chemistry Deoxyribonucleic acid Disruption DNA DNA - chemistry DNA - metabolism Immunoassay Immunoassay - methods Immunoassays Medical research Melting point Melting points Myocardial infarction Nanosensors Nanotechnology - methods Nucleic Acid Denaturation Proteins Streptavidin - analysis Troponin Troponin I
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