Effects of exosome-mediated delivery of myostatin propeptide on functional recovery of mdx mice

Duchenne muscular dystrophy (DMD) is a devastating disorder caused by loss of functional dystrophin protein, resulting in muscle wasting. Enhancing muscle growth by inhibiting myostatin, a growth factor negatively regulating skeletal muscle mass, is a promising approach to slow disease progression....

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Veröffentlicht in:	Biomaterials 2020-04, Vol.236, p.119826-119826, Article 119826
Hauptverfasser:	Ran, Ning, Gao, Xianjun, Dong, Xue, Li, Junjin, Lin, Caorui, Geng, Mengyuan, Yin, HaiFang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Duchenne muscular dystrophy Dystrophin Exosome Exosomes Mice Mice, Inbred mdx Muscle, Skeletal Muscular Dystrophy, Animal - drug therapy Muscular Dystrophy, Duchenne - drug therapy Myostatin Propeptide
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