Neutrophil to lymphocyte ratio as a potential predictive marker for treatment with pembrolizumab as a second line treatment in patients with non-small cell lung cancer

The aim of this multicentric retrospective study is to evaluate the predictive and prognostic performance of neutrophil to lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and their dynamics in patients with non-small cell lung cancer (NSCLC) treated with pembrolizumab as a second line. Patie...

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Veröffentlicht in:	BioScience Trends 2020/02/29, Vol.14(1), pp.48-55
Hauptverfasser:	Petrova, Mila P., Eneva, Mariyana I., Arabadjiev, Jeliazko I., Conev, Nikolay V., Dimitrova, Eleonora G., Koynov, Krassimir D., Karanikolova, Teodora S., Valev, Spartak S., Gencheva, Radostina B., Zhbantov, Georgi A., Ivanova, Anika I., Sarbianova, Iva I., Timcheva, Constanta V., Donev, Ivan S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies, Monoclonal, Humanized - therapeutic use B7-H1 Antigen Biomarkers Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - drug therapy Female Humans Immunotherapy Kaplan-Meier Estimate Lung Neoplasms - diagnosis Lung Neoplasms - drug therapy Lymphocytes - cytology Male Middle Aged neutrophil to lymphocyte ratio Neutrophils - cytology Platinum Compounds - therapeutic use predictive marker Proportional Hazards Models Retrospective Studies Survival Rate
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