Investigation of protective effects of apilarnil against lipopolysaccharide induced liver injury in rats via TLR 4/ HMGB-1/ NF-κB pathway

[Display omitted] •Apilarnil treatment reduced the histopathological changes caused by LPS.•Expressions of TLR4 signalling pathway increased by LPS administration were regulated by apilarnil treatment.•Apilarnil regulated increased apoptosis by LPS administration.•Apilarnil showed protective effect...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2020-05, Vol.125, p.109967-109967, Article 109967
Hauptverfasser:	Doğanyiğit, Züleyha, Okan, Aslı, Kaymak, Emin, Pandır, Dilek, Silici, Sibel
Format:	Artikel
Sprache:	eng
Schlagworte:	Apilarnil Apoptosis Inflammation Liver LPS Oxidative stress
Online-Zugang:	Volltext
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