Hydroxamic Acid‐Piperidine Conjugate is an Activated Catalyst for Lysine Acetylation under Physiological Conditions

Lysine acylation of proteins is an essential chemical reaction for posttranslational modification and as a means of protein modification in various applications. N,N‐Dimethyl‐4‐aminopyridine (DMAP) derivatives are widely‐used catalysts for lysine acylation of proteins; however, the DMAP moiety mostl...

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Veröffentlicht in:	Chemistry, an Asian journal an Asian journal, 2020-03, Vol.15 (6), p.833-839
Hauptverfasser:	Mizumoto, Shinsuke, Xi, Siqi, Fujiwara, Yusuke, Kawashima, Shigehiro A., Yamatsugu, Kenzo, Kanai, Motomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Acylation Basicity catalyst Catalysts Chemical reactions Chemistry Conjugates Deactivation Glutathione hydroxamic acid Lysine lysine acetylation Physiology Piperidine protein modifications Proteins
Online-Zugang:	Volltext
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