Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

Molecular mechanisms of ovarian aging and female age-related fertility decline remain unclear. We surveyed the single-cell transcriptomic landscape of ovaries from young and aged non-human primates (NHPs) and identified seven ovarian cell types with distinct gene-expression signatures, including ooc...

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Veröffentlicht in:	Cell 2020-02, Vol.180 (3), p.585-600.e19
Hauptverfasser:	Wang, Si, Zheng, Yuxuan, Li, Jingyi, Yu, Yang, Zhang, Weiqi, Song, Moshi, Liu, Zunpeng, Min, Zheying, Hu, Huifang, Jing, Ying, He, Xiaojuan, Sun, Liang, Ma, Lifang, Esteban, Concepcion Rodriguez, Chan, Piu, Qiao, Jie, Zhou, Qi, Izpisua Belmonte, Juan Carlos, Qu, Jing, Tang, Fuchou, Liu, Guang-Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	aging antioxidant gene granulosa cell oocyte ovary primate single-cell RNA sequencing
Online-Zugang:	Volltext
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