Transcriptomic landscape, gene signatures and regulatory profile of aging in the human brain

The molecular characteristics of aging that lead to increased disease susceptibility remain poorly understood. Here we present a transcriptomic profile of the human brain associated with age and aging, derived from a systematic integrative analysis of four independent cohorts of genome-wide expressi...

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Veröffentlicht in:	Biochimica et biophysica acta. Gene regulatory mechanisms 2020-06, Vol.1863 (6), p.194491-194491, Article 194491
Hauptverfasser:	González-Velasco, Oscar, Papy-García, Dulce, Le Douaron, Gael, Sánchez-Santos, José M., De Las Rivas, Javier
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Biochemistry & Molecular Biology Biological age Biophysics Brain Cerebral cortex Life Sciences & Biomedicine Machine learning Science & Technology Transcriptomics
Online-Zugang:	Volltext
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