Recommendations for clinical laboratory testing for protein C deficiency, for the subcommittee on plasma coagulation inhibitors of the ISTH

Inherited protein C (PC) deficiency increases risk of venous thromboembolism (VTE) by 5 to 10‐fold in thrombosis‐prone families; however, heterozygous PC deficiency alone does not determine that a subject has thrombophilia. Protein C deficient subjects, who lack additional inherited risk factors suc...

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