Nonclassical Monocytes Sense Hypoxia, Regulate Pulmonary Vascular Remodeling, and Promote Pulmonary Hypertension

An increasing body of evidence suggests that bone marrow-derived myeloid cells play a critical role in the pathophysiology of pulmonary hypertension (PH). However, the true requirement for myeloid cells in PH development has not been demonstrated, and a specific disease-promoting myeloid cell popula...

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Veröffentlicht in:The Journal of immunology (1950) 2020-03, Vol.204 (6), p.1474-1485
Hauptverfasser: Yu, Yen-Rei A, Malakhau, Yuryi, Yu, Chen-Hsin A, Phelan, Stefan-Laural J, Cumming, R Ian, Kan, Matthew J, Mao, Lan, Rajagopal, Sudarshan, Piantadosi, Claude A, Gunn, Michael D
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Sprache:eng
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