Protective effect of D-pinitol on the experimental spinal cord injury in rats

Spinal cord injury (SCI) is the major cause of the spinal damage affecting motor and sensory function. Thus, the present study was conducted to investigate the effect of D-pinitol (PN) on spinal cord injury in rats. The PN showed to recover motor function near to normal via modulating oxidative stre...

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Veröffentlicht in:	Metabolic brain disease 2020-03, Vol.35 (3), p.473-482
Hauptverfasser:	An, Yan, Li, Jianing, Liu, Yajun, Fan, Mingxing, Tian, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Bcl-2 protein Biochemistry Biomedical and Life Sciences Biomedicine Caspase-1 Inflammation Inflammation - drug therapy Inflammation - metabolism Inflammation - physiopathology Inflammatory response Injuries Inositol - analogs & derivatives Inositol - pharmacology Inositol - therapeutic use Liquid oxygen LOX-1 protein Male MAP kinase Metabolic Diseases Modulation Neurology Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Neurosciences NF-kappa B - metabolism Nitric-oxide synthase Oncology Original Article Oxidative stress Oxidative Stress - drug effects Proto-Oncogene Proteins c-bcl-2 - metabolism Rats Rats, Sprague-Dawley Recovery of Function - drug effects Recovery of Function - physiology Signal Transduction - drug effects Spinal Cord - drug effects Spinal Cord - metabolism Spinal Cord - physiopathology Spinal cord injuries Spinal Cord Injuries - drug therapy Spinal Cord Injuries - metabolism Spinal Cord Injuries - physiopathology Tumor necrosis factor-α
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