The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution

Because the lymph node (LN) is a critical organ for inducing immune responses against pathogens and cancers, the transport of immune functional molecules such as antigens and adjuvants to LNs by delivery systems is a useful strategy for the effective outcome of an immune response. The size and charg...

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Veröffentlicht in:Molecular pharmaceutics 2020-03, Vol.17 (3), p.944-953
Hauptverfasser: Nakamura, Takashi, Kawai, Minori, Sato, Yusuke, Maeki, Masatoshi, Tokeshi, Manabu, Harashima, Hideyoshi
Format: Artikel
Sprache:eng
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