Osteocytes' expression of the PTH/PTHrP receptor has differing effects on endocortical and periosteal bone formation during adenine-induced CKD

Osteocytes play a key role in the pathophysiology of chronic kidney disease (CKD). However, the extent to which osteocytes contribute to abnormalities in bone turnover due to excessive levels of parathyroid hormone (PTH) remains poorly understood. The purpose of this study was to determine the exten...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2020-04, Vol.133, p.115186-115186, Article 115186
Hauptverfasser:	Gardinier, Joseph D., Daly-Seiler, Conor S., Zhang, Chunbin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Animals CKD Female Mice Osteocytes Osteogenesis Parathyroid Hormone Parathyroid Hormone-Related Protein PTH PTH receptor Receptor, Parathyroid Hormone, Type 1 Renal Insufficiency, Chronic - chemically induced Renal osteodystrophy
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