Maternal hypoxia developmentally programs low podocyte endowment in male, but not female offspring

Fetal hypoxia is a common complication of pregnancy. We have previously reported that maternal hypoxia in late gestation in mice gives rise to male offspring with reduced nephron number, while females have normal nephron number. Male offspring later develop proteinuria and renal pathology, including...

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Veröffentlicht in:Anatomical record (Hoboken, N.J. : 2007) N.J. : 2007), 2020-10, Vol.303 (10), p.2668-2678
Hauptverfasser: Gonçalves, Gessica D., Walton, Sarah L., Gazzard, Sarah E., Wolde, James, Mathias, Paulo C. F., Moritz, Karen M., Cullen‐McEwen, Luise A., Bertram, John F.
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Sprache:eng
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