Rotenone‐induced reactive oxygen species signal the recruitment of STAT3 to mitochondria

STAT3, a transcription factor involved in various physiological and pathological processes, is also present in mitochondria. Mitochondrial STAT3 regulates complex I activity and reactive oxygen species (ROS) production, yet the mechanisms governing its translocation to mitochondria remain poorly und...

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Veröffentlicht in:	FEBS letters 2020-05, Vol.594 (9), p.1403-1412
Hauptverfasser:	Mohammed, Fareed, Gorla, Madhavi, Bisoyi, Vandana, Tammineni, Prasad, Sepuri, Naresh Babu V.
Format:	Artikel
Sprache:	eng
Schlagworte:	HeLa Cells Humans mitochondria Mitochondria - drug effects Mitochondria - metabolism oxidative stress Oxidative Stress - drug effects Oxidative Stress - physiology Phosphorylation - drug effects Reactive Oxygen Species - metabolism ROS Rotenone - pharmacology Serine - metabolism STAT3 STAT3 Transcription Factor - genetics STAT3 Transcription Factor - metabolism
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