Improving the in-vivo biological activity of fingolimod loaded PHBV nanoparticles by using hydrophobically modified alginate

Uncontrolled distribution of nanoparticles (NPs) within the body can significantly decrease the efficiency of drug therapy and is considered among the main restrictions of NPs application. The aim of this study was to develop a depot combination delivery system (CDS) containing fingolimod loaded pol...

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Veröffentlicht in:	Drug development and industrial pharmacy 2020-02, Vol.46 (2), p.318-328
Hauptverfasser:	Rezaie Shirmard, Leila, Ghofrani, Mahdieh, Bahari Javan, Nika, Bayrami, Samane, Tavassoli, Abdollah, Rezaie, Amir, Amini, Mohsen, Kebriaee-zadeh, Abbas, Rouini, Mohammad-Reza, Dinarvand, Rassoul, Rafiee-Tehrani, Morteza, Dorkoosh, Farid Abedin
Format:	Artikel
Sprache:	eng
Schlagworte:	alginate Combination delivery system fingolimod PHBV nanoparticles prolonged release
Online-Zugang:	Volltext
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