Transcompp: understanding phenotypic plasticity by estimating Markov transition rates for cell state transitions

Abstract Motivation Gradual population-level changes in tissues can be driven by stochastic plasticity, meaning rare stochastic transitions of single-cell phenotype. Quantifying the rates of these stochastic transitions requires time-intensive experiments, and analysis is generally confounded by sim...

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Veröffentlicht in:	Bioinformatics 2020-05, Vol.36 (9), p.2813-2820
Hauptverfasser:	Jagannathan, N Suhas, Ihsan, Mario O, Kin, Xiao Xuan, Welsch, Roy E, Clément, Marie-Véronique, Tucker-Kellogg, Lisa
Format:	Artikel
Sprache:	eng
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