Neutrophils as emerging therapeutic targets

Neutrophils are the most abundant circulating leukocytes, being the first line of defence against bacterial and fungal infections. However, neutrophils also contribute to tissue damage during various autoimmune and inflammatory diseases, and play important roles in cancer progression. The intimate b...

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Veröffentlicht in:	Nature reviews. Drug discovery 2020-04, Vol.19 (4), p.253-275
Hauptverfasser:	Németh, Tamás, Sperandio, Markus, Mócsai, Attila
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154 631/250/249/1313 631/250/2504/223/1699 631/250/255 631/67 692/699/75 Animals Autoimmune Diseases - immunology Bacterial infections Biomedical and Life Sciences Biomedicine Biotechnology Cancer Research Congenital diseases Cytokines Drug targeting Drug therapy Forecasts and trends Health aspects Homeostasis Humans Infections Inflammation Inflammation - immunology Kinases Leukocytes - immunology Lupus Medicinal Chemistry Molecular Medicine Mutation Neutropenia Neutrophils Neutrophils - immunology Pathogenesis Pharmacology/Toxicology Review Article Rheumatoid arthritis Trends
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